Emva kokususwa kwee-ovari okanye inkqubo enzima yokuphuma kwindoda, umfazi unokumiselwa izidakamizwa zokutshintsha i-hormone. Bathucula umgangatho wobomi, kodwa i-hormone yonyango yokuguqula (HRT) yabasetyhini inokumiselwa kuphela izibonakaliso ezithile:
- kunye nokuphumula kokuqala (ukuya kwiminyaka engama-40);
- emva kokususwa kwee-ovari;
- ngokungahambi;
- i-hormone yonyango ekutshintsheni kwimijikelezo yesimo sokuqala yokuya esikhathini eneminyaka engama-40 ukuya kwengu-50, kunye nenkqubo enzima yokuphuma kwesisu;
- xa ususa isibeleko ngamacwecwe alondoloziweyo;
- kunye neengxaki zokunqamuka kwesisu (i-osteoporosis, atherosclerosis, i-atrophic vaginitis).
Kodwa iziyobisi ze-hormone zonyango (HRT) zineenkcukacha ezingqinelanayo:
- izicubu zesisu, ama-ovari okanye iintloko zeentloko;
- i-cirrhosis yesibindi, ukuhluleka kwesibindi;
- izifo;
- uhlobo olunzulu lwesifo sikashukela;
- ukuphuma kwintsholongwane ye-uterine ye-etiology;
- Musa ukucebisa ukusetyenziswa kweziyobisi kwi-endometriosis, i-fibroids yesisu.
Iimveliso kunye neengxaki ze-hormonal substitution
Abafazi basoloko bekwesaba ukutyunjwa kwamahomoni, ukuba kukho ukuphuma kwimizi, i-hormone yonyango yokutshintsha ingathatha indawo kunye ne-phytopreparations, efana nokusebenza kwimizi-hormone yesini. Kodwa ngamanye amayeza i-hormone therapy iboniswa kwintombi kwaye inezinto ezininzi ezintle. Ezi ziquka ukuphucula impilo yonke, ukulala nokusebenza kwengqondo. Ngaphantsi kweempembelelo ze-hormone yonyango, ukunyuswa kwegazi kuyancipha, umsebenzi weentliziyo uphucula, izinga leentliziyo liqhelekile, isimo se-vascular siphucula (umngcipheko wokuhlaselwa kwintliziyo kunye nesifo soxinzelelo sinciphisa kakhulu). IHormonotherapy kwabasetyhini ngexesha lokuphuphuma kwesisu kuphucula ukusebenza kwe-thyroid gland, kunciphisa umngcipheko we-osteoporosis, kuphucula imeko yesikhumba kunye neembumba zamanqatha (kubandakanya amalungu omzimba).
Imiphumo emibi ye-hormone ye-substitution treatment iyimpawu ezifana ne-premenstrual syndrome: iintloko, ukukhubeka, ukuxhamla kweengqungquthela zamathambo. Kungase kube nokuphuma kwamanzi omzimba ongasebenzi , apho uviwo oluvakalayo luyimfuneko ukuba lukhuphe izicubu ezinzima zesisu. Kukho ukutshintshwa kwesikhumba (amaninzi aphezulu, ubomvu nokucaphukisa), iinwele (i-hirsutism xa uthatha i-testosterone).
I-Hormone yonyango lokutshintshwa: iziyobisi
I-hormone yonyango yokutshintshwa isebenzise iziyobisi eziqukethe i-estrogens kuphela okanye i-progesterone, kwakunye nokudibanisa kwama-hormone zombini. Ukuba kungekhona kuphela ama-ovari asuswe, kodwa kunye nesisu, israjeni yonyango isetyenziselwa unyango oluthathe indawo. Ukususela kumalungiselelo aqukethe i-estrogens kuphela, kaninzi iincoma ukulungiselela ama-Estrofem, Esterozhel, Proginova. Ukulungiselela okuqulethe kuphela ama-progesterone afana ne-Utrozhestan, Dufaston, iProgesterone. Idibeneyo
Iingxoxo ze-hormone unyango olutshintsho lunokuthi lube yi-phytoestrogens, ezenzweni zabo zifana ne-estrogens yabasetyhini, kodwa zibuthathaka kakhulu ngokwemandla yempembelelo. Ngenxa yale njongo, akusebenzi nje kuphela iimveliso ezizityebi kwi-phytoestroics, kodwa i-phytopreparations kwizityalo ezizityebi kuzo (i-clover ebomvu yilezo zityalo).