Enye yama-antigens eqela legazi yiR Rh factor. Ubukho bayo bubonisa ukuba i-rhesus yakho iyanceda. Ukuba akukho i-antigen, iR Rh ayibi, kwaye oku kunokuba nefuthe elibi kwixesha lakho lokukhulelwa. Ngoko ke, abantu abaneRhesus enhle abanakuze bakhumbule ngayo, ngelixa umfazi onesifo esingenanto yegazi ufanele azi ukuba ngexesha lokukhulelwa, kunokubakho ingozi yokuxabana kweRh.
I-Rhesus-impikiswano ibonakaliswe ngenxa ye-ingress ye-erythrocyte yangaphandle kwigazi lomntu, eliqhutyelwa yiiprotheni zenkqubo yeRhesus. Kwi-immune system, bengaphandle, kwaye ngenxa yoko, inkqubo yokuvelisa izifo ezikhuselekileyo iqala. Xa ukukhulelwa kuholele kuye, kukho i-rhesus engafanelekanga kwintombi kunye noyise womntwana ontle. Zonke ezinye izihlanganisi azikho kwi-Rhesus-conflict.
Nangona kunjalo, nangona iRhesus engalunganga, ucwangciso olupheleleyo lokukhulelwa lunokwenzeka kumama. Okokuqala, ukukhusela okufanelekileyo kukuvumela ukuba kungabikho imiphumo ye-Rh-conflict, kwaye, okwesibini, i-Rh yeyona nto ingalunganga, nokuba ekukhulelweni kwesibili, akukho konke okukhokelela ekuphuhlisweni kwayo.
Ama-antibodies aseRhesus yilezo zixhobo zeprotheni eziveliswa kumzimba womama xa zingeniswa kwi-Rh-positive cells cells ebomvu. Xa zifumaneka kwigazi lomama, ukuxilongwa kwenzelwa-i-Rh-senitization. Oku kutyhilwa xa ukupheliswa kwexesha lokuzikhupha okanye ukufakelwa komzimba kubangelwa i-rhesus engafanelekanga kumfazi. Kwakhona iindiza ezinokuthi zenzeke ngexesha lokukhulelwa kokuqala, xa igazi lomntwana onesifo esihle se-rhesus singena egazini lomfazi onomrhesus ombi emva kokuzalwa.
Kwezinye iimeko, ukukhuthazwa kunokwenzeka kwiinqanaba zokuqala, kuba izixhobo zokulwa nazo zivela kwigazi le-fetal, ukususela kwiveki yesi-7 yokukhulelwa. Nangona ngokuqhelekileyo ukukhulelwa kokuqala kwabasetyhini abane-Rh factor kungenziwa ngaphandle kweengxaki, ukuba ngaphambili kwakungekho ukukhuthaza umzimba.
Ukwaziswa kweRhesus kunokuphuhliswa, kwimeko yokukhutshwa ngokusesikweni kwipentecenta, kwaye nokuba ukuzalwa kokuqala kwakuhamba kunye nokuphuma kwegazi okanye owesifazane obelethayo yi-cearean. Kwaye, oku, kwenzeka oko kwimeko yesibini (yesithathu) yokukhulelwa kunye ne-rhesus engalunganga kumama. Oku kubangelwa ukuphakama okuphezulu ukuba amangqamuzana egazi abomvu aseRhesus angenayo igazi lomama. Kwaye ngoko, i-Rhesus antibodies iya kuqala ukwenza.
Ngenxa yokuba i-immune system yomama ene- rhesus embi ngexesha lokukhulelwa kwenzeka ngeeseli ezibomvu zeeseli (i-Rh-positive) okokuqala, izikhuhlane ze-antibodies azivelwanga ngokukhulu. Kwaye ku-10% yabasetyhini emva kokukhulelwa kokuqala kukho ugonyo. Ngaloo ndlela, ukuba ibhinqa elingenanto iRhesus igweme u-Rhesus ukugonywa, ngoko ekukhulelweni kwe sibini ukubonakala kokubukeka kwayo kuya kuphinda kube ngu-10%. Ngenxa yoko, kubaluleke kakhulu nge-rhesus engafanelekanga kwibhinqa ngaphambi kokuqala kokukhulelwa okwesibini ukudlulisa uhlalutyo ukuze kuhlolwe ubukho be-antibodies egazini. Ngalesi sikhathi, kufuneka ukuba sele ebhaliswe kunye neziko lempilo. Kwilandelayo emva koko, kwaye unokwenza uviwo olongezelelweyo.
Kwakhona, nge-rhesus engalunganga ngaphambi kokucwangcisa ukukhulelwa okwesibini, kubalulekile ukufumanisa ukuba i-Rh iyintoni umntwana wakho wokuqala.
Le nkxalabo, njengento yokukhulelwa ngokukhawuleza kwabasetyhini abane-rhesus engafanelekanga, ngokuqhelekileyo iyenzeka ngexesha lokuqala lokukhulelwa (ukuya kwiiveki ezili-14). Ukufa komntwana emva kokuzalwa komntwana emva kweveki ezingama-28 kunokwenzeka.
Phakathi kwamanyathelo athatywayo ngexesha lokukhulelwa komfazi onesifo esingenanto, kuya kubakho ukubandakanya, ukongeza kwenkqubo eyenza ukucocwa kwamagciwane, kunye nokuxelwa kwegazi kwangaphakathi kwegazi.