I-Allopurinol kunye neempawu zayo ziyeza amayeza anqunywe ngokunyuka kwe-uric acid emzimbeni-hyperuricemia. Esi sifo sivame ukukhokelela kwisifo. Kunconywa amayeza kwizigulana ezingenakulawulwa kuphela ngokutya.
Iipilisi ze-Allopurinol nazo zichazwe kubantu abaye babulala izifo zetye kunye nephropathy. Isetyenziselwa abantu abadala kunye nabantwana abaneminyaka engaphezu kwe-15 ubudala abanempawu yezi zifo ezichasene nemvelaphi ye- leukemia , kunye nabantu abanokukhubazeka kwe-enzymatic congenital.
Indlela yokutshintsha i-Allopurinol nge gout?
Iingqungquthela zesakhiwo se-Allopurinol:
- Allpol;
- Alopron;
- Sanphipurol.
Icandelo eliphambili li-oxypurinol, elikhupha ukuguqulwa kwe-hypoxanthine kwi-xanthine, kwaye emva kwe-uric acid. Ngoxa uncediswa iziyobisi, izinga lokugqibela kumchamo kunye nenkqubo yokujikeleza iyancipha. Oku kukuthintela ukuqokelela kwamakristal e-urate emzimbeni kwaye kukhuthaza ukuhlaziywa kwawo. Inani le-asidi liqala ukunciphisa kuphela ngosuku lwesine lokuthatha amayeza. Isiphumo esiphezulu siphumelele emva kweveki ezimbini.
I-Purinol nayo isalathisi esakhiweyo se-Allopurinol. Ngethuba lokulawulwa kweziyobisi, i-synthesis ye-uric acid iyancipha, ekhokelela ekunciphiseni kwayo kwi-media media yomzimba. Ukongezelela, iifomethi zokuhlala ezikhoyo sele zichithwa kwaye ukuveliswa kwakhona kwazo kwiintso kunye nezicubu zithintelwe. Xa ufumana i-Purinol, ukukhutshwa kwe-xanthine kunye ne-hypoxanthine kumchamo kwanda. Impembelelo yeliza lixhomekeke kwiqondo elimiselweyo.
Ukungqinelana nokusetyenziswa kwe-Allopurinol kunye nezifana zayo
I-Allopurinol kunye nee-analogs zayo, ezinqunyelwe i- gout , zineenkcukacha ezingqinelanayo, ezibonakaliswe kwiimeko ezithile. Ngoko, umzekelo, kukho izigulane ezakha i-bradycardia kunye nomfutho wegazi. Kwezinye iimeko, kwakukho:
- isicaphulo kunye nokuhlanza;
- isifo sohudo;
- i hepatitis;
- stomatitis;
- steatorrhea.
Phantse njalo le nto yayihamba kunye:
- buthathaka;
- ukhathala okwandisiweyo;
- intloko;
- ataxia;
- ukungcola.
Ngaphantsi kaninzi-ukuphulwa kombono kunye neengcamango zengcamango, ukuphazamiseka kwegazi, i-cataracts, ukudandatheka kunye ne-coma.
Ngethuba lokunyanga, izigulane ezaba neempembelelo ezinobungozi kwesikhumba, i-hyperemia, i-pruritus, i-fever ne-fever nazo zaphawulwa. Kwezinye iimeko, abantu bavelisa i-furunculosis kunye neenwele ezichaziweyo.
Ukuba kuyimfuneko, iingcaphephe zincoma ukuthatha i-Allopurinol kuphela, kwaye ukuba ufuna ukuyibeka endaweni ethile ngento ethile, kufuneka usebenzise kuphela iimpawu ezifanayo. Ngaphandle koko, kunokuchaphazela kakubi umsebenzi wesibindi kunye nomzimba wonke.