I-Glucocorticosteroid yinto engumthombo wendalo okanye owenziweyo. Libhekisela kwi-subclass yama-hormone kwi-correnx ye-adrenal. Ukulungiselelwa kwiqela le-glucocorticosteroids linomphumela wokuzikhusela komzimba kwaye kwandiswe ukwakheka kwe-glucose kwisibindi, ngoko bahlala besetyenziselwa unyango lwezifo ezahlukahlukeneyo.
I-glucocorticosteroids ichaphazela njani umzimba?
Ukubaluleka kwezinto eziphilayo ezibalulekileyo ze-glucocorticosteroids kukunyusa kakhulu ukwanda komzimba wokuxinezeleka. La mayeza asetshenziselwa ukunqanda uhlaselo lwe-immune system, olujoliswe kumzimba wakho. Le meko ivela xa izidumbu zihamba, izidumbu ezibi kunye nezifo ezizimele. Ukongeza, i-glucocorticosteroids ithintela i-mineral, amanzi, i-carbohydrate kunye neprotein yamatabolism. Ziye zisetyenziswe njengama-anti-inflammatory, antitoxic and desensitizing agents. Kulo unyango lungasetyenziselwa iifom ezinjalo:
- intranasal;
- parenteral;
- inhaled glucocorticosteroids.
La mayeza anakho ukuphakamisa uxinzelelo lwegazi. Kuzaliswa ngenxa yokwanda okwenziwe ukukhululwa kwe-adrenaline, kunye nokunciphisa umbane wemigodi yegazi. Oku kuvumela ukusebenzisa i-glucocorticosteroids ukujongana namazwi okutshitshiswa kwiimeko ezibucayi.
Amagama eziyobisi evela kwiqela le-glucocorticosteroids
Kukho amalungiselelo ambalwa ukusuka kwiqela le-glucocorticosteroids, kwaye amagama abo baqhelana nabantu abaninzi, kuba basebenziselwa ukuphatha izifo eziqhelekileyo. Izixhobo ezidumileyo zolu hlobo:
- I-Belogen - ukhilimu okanye i-ointment yokusetyenziswa kwangaphandle. Isetyenziselwa i- eczema , isasaze i-neurodermatitis, i-atopic kunye nezinye i-dermatitis.
- I-Sherisolone - iipilisi ezinxulumene ne-glucocorticosteroids. Kusetyenziswa ukunyanga i- scleroderma , i-nodular periarteritis, i-rheumatoid arthritis.
- I-Cortonisol i-aerosol esetyenziswa kwi-colitis, isifo sikaCrohn, i-proctitis kunye nesifo se-ulcerative colitis.
- I-Solu Medrol yi-lyophilizate yokulungiselela isisombululo okanye ukumiswa kwamanzi ukujova. Isetyenziselwa ukutshisa kunye nokuphazamiseka, ukuphendula ngokuthe tye.
Isilwanyana ngasinye esivela kuluhlu lwe-glucocorticosteroids sinokuchasene. Cishe nayiphi na enye ayifanele isetyenziswe kwisifo sikashukela, isifo seCushing, i-thromboembolism kunye nokungaphumeleli kwintlungu. Akukho imfuneko yokwenza unyango nge-glucocorticosteroids ngethuba elisebenzayo lesifo sofuba nesifo se-syphilis.