I-edema kaQuincke yimeko ekhuselekileyo, apho kukho ukuvuvukala okukhulu kwezinto zesikhumba kunye namafutha angaphantsi, ngamanye amaxesha kuququzelele inkqubo ye-pathological membranes. Esi sifo saqanjwa ngamagqirha uG. Quinke, owathi wachaza okokuqala ngo-1882. Igama lesibili lokukhubazeka li-angioedema.
I-Edema ye-Quincke - izizathu ze
Njengemingxuma, i-edema kaQuincke idibene ne-vasodilation kunye nokunyuka kokubonakala kwabo kwi-blood flow medium, kodwa kulo mzekelo, ukukhukhuma kubonakala kungekho nje, kodwa kwiindawo ezinzulu zolusu, izicubu ezinamaqabunga, i-fat layer layer. Ukuqokelela kwezicubu ze-interstitial fluid yangena kwi-edema. Ukwandiswa kwe-Vascular kunye nokwanda kwimizimba yabo ngenxa yokukhutshwa kwezinto eziphilayo (bradykinin, histamine, njl), eyenzeka ngenxa yokuphendula komzimba phantsi kwefuthe lezinto ezithile.
I-angioedema inokungafani, kwaye idla ngokubangela izizathu ezilandelayo:
- isenzo sezilwanyana;
- iziphazamiso zokusebenza zenkqubo yokutya;
- ukuphazamiseka kwenkqubo ye-endocrine;
- ukuthatha imithi (imithi yokukhulelwa ngomlomo, i-analgesics, i-antibiotics, i-ACE inhibitors, iigcino, i-serums);
- izifo zesifo;
- izifo zegazi;
- izilonda zentsholongwane kunye nezifo zomzimba;
- izifo ezibangelwa ngumzimba emzimbeni;
- ukungafani kwongcinezelo lwangaphakathi, ubushushu bomoya, njl njl.
I-edema yeHereditary yaseQuincke
Enye yeentlobo ezingabonakaliyo ze-pathology ezicatshangelwayo yi-angioedem yefa, ehambelana nokuphazamiseka kwenkqubo ehambelana nelifa. Inkqubo yenkxaso, ehlanganisa ukudibanisa izakhiwo zeprotheni, ibalulekileyo yecandelo le-immune system, elibandakanyekayo ekuvukeleni nasekuphenduleni. Umgaqo wale nkqubo ngenxa yeenzyme, phakathi kwabo-inhibitor C1. Xa le enzyme ingenalutho, ukungalawulwa komthetho kuzalisekisa ukusebenza kunye nokukhululeka kwezinto ezibangele i-edema.
Imiqondiso yokuqala ye-edema edematous edema inokubonakala nakumntwana, kodwa kwiimeko ezininzi kwixesha elikhulayo okanye kwixesha eliphakathi. Ukuphuhliswa kokuhlaselwa kudla ngokulandelwa ngenye into ephazamisayo:
- sulelo;
- uxinzelelo lwengqondo;
- yokuhlinzwa;
- nzakala;
- ukuthatha nayiphina imithi.
I-Edema ye-Quincke ye-Edema
I-Alergies iyona nto ibangele kakhulu ye-angioedema. Ukongezelela, isiqhelo sesifo sidibaniswa nezinye izifo zendalo - i-pollinosis, i-asthma ye-bronchial, i-urticaria, i- atopic dermatitis , njl. Ukuba indlela yokubonakala kwentsholongwane ekubhekiselele kuyo ingxaki yokungathandabuzeki, i-edema ka-Quincke iyindlela yokuphendula kwisimo eshukumisayo. Njengoko izinto ezinokumangalisa zingaba:
- iimveliso zokutya kunye neezongezo kubo (intlanzi, izithelo zegritrus, ubusi, iinqatha, ishokoleta, i-flavour, i-colorants, i-conservatives, njl);
- impova ;
- Iintsiba kunye neentaka zeentaka;
- izinwele zezilwanyana ;
- utyhefu kunye nemathambo ezinambuzane;
- ngothuli;
- iindlela zeekhemikhali zeemveliso zekhaya;
- ukukhanya kwelanga;
- ukushisa okuphezulu okanye okuphantsi;
- mayeza, njl
Idiopathic Quincke's Edema
Kukho i-angioedema ye-idiopathiki, engenakucaciswa. Kule meko, ukuhlaselwa kwempendulo enganeleyo kwimizimba ayikwazi ukudibaniswa nayo nayiphi na into echaziweyo. Le ndlela ye-pathology, iingcali ezininzi zibiza ngokuba yingozi kakhulu, kuba, ngokungazi into ebangela ukuvuvukala, awukwazi ukunqanda ukubonakala kwayo kunye nokuphelisa i-factor-culprit.
Iimpawu ze-Edema ze-Quincke
Iimpawu ze-Angioedema zithethwa, okwenza kunzima ukungayithobeli ingqalelo, kubandakanyeka kuba banako ukudala ukungahambi kakuhle kunye nokunyusa ukusebenza kwamalungu athile omzimba. I-Edema kwindawo echaphazelekayo ibonakala ngeso lesiso, isikhumba (okanye i-membrane ye-mucous) ibonakala igubha, ngelixa lingatshintshi i-hue yayo (emva koko iyakwazi ukuguquka emhlophe).
Iindawo eziqhelekileyo zendawo yokuhlala zi:
- umntu;
- umlomo womlomo;
- ulwimi;
- larynx;
- umkhondo;
- entanyeni;
- izitho zangasese;
- izitho ezingaphezulu kunye nezantsi;
- Izitho zangaphakathi (isisu, isisu, isantya, i-meninges, njl.).
Kwiindawo ezichaphazelekayo, izigulane zifumana ukuxhatshazwa, ukuqina, ukunyamezela, ukutshisa, ukubetha, ukungabonakali - ukubetha. Iziphathamandla zangaphakathi ezichaphazelekayo zingabangela iziganeko ezifana nobuhlungu besisu, isicathulo, ukuhlanza, urhudo, umchamo, intloko, njl njl. Isifo sokuphefumula esichaphazelekayo senziwa ngokubonakala ngathi ukuphefumula, ukukhwehlela, ukuphefumula, kungakhupha ukuphefumula. I-quema ye-quema ye-edema ihlala ihamba kunye nokubonakala kwimibala ebomvu. Ukunciphisa ubuqhophololo kunokuba ngumlilo omncinci kunye nokutshisa.
Kwenzeka ngokukhawuleza njani ivelise i-edema yeQuincke?
Kwiimeko ezininzi, ukuba isenzo sokunyanga sithatha inxaxheba kwindlela yokuphuhlisa, ukukhukhuma kukaQuincke kubonakala ngokukhawuleza, kuqala ngokukhawuleza. Iimpawu zikhula phakathi kwemizuzu engama-5-30, kwaye isilungiso kufuneka silindele emva kweeyure eziliqela okanye iintsuku ezingama-2-3. Ngokwemvelo engeyiyo i-pathology, ubuqhophololo buvame ukukhula ngaphakathi kweeyure ezingama-2-3 kwaye buyalala emva kweentsuku ezingama-2-3.
I-Angioedema ye-larynx
I-Angioedema yomqala ibeka ingozi enkulu emzimbeni kwaye inokubangela ukuba kufakwe ngokukhawuleza. Kwimizuzu embalwa nje, i-airways ingavalwa ngokupheleleyo ngenxa yeethambo ezivuvukileyo. Iimpawu ezinobungozi, okumele zibe sisizathu esiphuthumayo sokubiza i-ambulensi, ngaba:
- isikhumba esibomvu ebusweni;
- ukuvutha ngamandla;
- ukuphosa okuphambili kwixinzelelo legazi;
- zixhala.
I-Angioedema yobuso
Ekubeni ubuso, i-edema yeQuincke, isithombeni sayo sibonisa uphawu oluphawulekayo, luhlala luhlala kwiibophezelo, izihlathi, impumlo, imilomo. Ngexesha elifanayo, i-slits yeeyame ingancinci, iinkozo ze-nasolabial zingahlanjululwa, enye okanye zombini imlomo ingakhula ngokukhawuleza ngobukhulu. I-Edema iyakwazi ukufudukela kwindawo yentamo, ifuthe i-airways kwaye ibambe ukufikelela komoya. Ngako oko, ukuvuvukala kweQuincke ebusweni kufuneka kumiswe ngokukhawuleza.
I-Angioedema yeemida
Imiqondiso ye-edema ka-Quincke, ehlala kwizandla kunye neenyawo, ihlala ibonwa ngasemva kweenyawo kunye neentende. Olu hlobo lokusabela aluqhelekanga kunokuba luchazwe ngasentla kwaye aluyiyo ingozi ethile ekusebenzeni komzimba, nangona kubangela ukuphazamiseka okukhulu. Ukongeza kokubonakala kweendawo ezinqamlekileyo zokudibanisa kwizitho, ulusu luyakwazi ukufumana i-bluish tint.
Yintoni enokuyenza ngokukhukhumeza kukaQuincke?
Izigulane eziye zenza isiqhelo sokukhukhumaza ngokukhawuleza kwesinye okanye enye inxalenye yomzimba ubuncinane kanye kanye ebomini babo kufuneka bazi ukuba kususwe ukuvuvukala kweQuincke, kuba i-pathology ingavela kwakhona ngokukhawuleza. Okokuqala, kufuneka ubize i-ambulensi, ngakumbi xa kukho ukuvuvukala kwindlela yokuhamba okanye kukho ukukrokra kwendawo yokukhubazeka kwizitho zangaphakathi. Ngaphambi kokufika kwabasebenzi bezempilo, amanyathelo okuncedisa kuqala kufuneka athathwe.
Edema Quincke - Uncedo lokuqala
Ukunyamekela ngokukhawuleza kokukhukhumeza kukaQuinck, okungafumaneka phambi kokuba i-ambulensi ifike, iquka ezi zilandelayo:
- Ukuqhawulwa kwexhoba ukususela kwisenzo sesiphumo (ukuba sifakwe).
- Ukubonelela ngokufikelela kwamahala okuhlambulula umoya.
- Ukukhululwa kwesigulane kwizinto ezinxibayo kunye nezixhobo.
- Ukulungiswa kwesigulane kwisigxina se-semi-sitting okanye indawo yokuhlala ukulungiselela ukuphefumula.
- Ukugcina indawo ezolile, ukukhusela ukwesaba.
- Ukunyanzeliswa kokubanda okubandayo kwiziko lesilonda.
- Ukubonelela ukusela kakhulu (mhlawumbi i-alkaline).
- Amachiza: amaconsi e-vasoconstrictive ekhaleni (uNaphthyzin, Otryvin), i-antihistamines (i-Fenistil, i-Suprastin) kunye neentlobo (Enterosgel, Atoxil) ngaphakathi.
Amanyathelo angentla apha, anika uncedo ngokuvuvukala kweQuincke, ayimfuneko, okokuqala, xa ebonwa:
- ukuvuvuka kwempumlo;
- ukuvuvukala komlomo;
- ukuvuvukala kwe-mucosa yomlomo;
- ukuvuvukala komqala, i-larynx;
- ukuvuvuka kwentamo;
- i-edema yezitho zangaphakathi.
Indlela yokuphatha i-angioedema?
Amachiza angxamisekileyo ukuphelisa i-edema enzima kunye nokubuyisela imisebenzi ebalulekileyo ingaquka ukusetyenziswa kwezi ziyobisi:
- I-Adrenaline - kunye nokuncipha kwexinzelelo lwegazi;
- I-Prednisolone, iDexamethasone - kwimeko ye-edema kaQuinck, ukubonakaliswa okubalulekileyo kususwe;
- I-Glucose, i-Haemodez, i-Reopoliglyukin-ukuphelisa ukutshatyalaliswa kunye nokukhishwa kwe-toxin;
- I-Dimedrol, i-injection ye-Suprastin
- I-Furosemide, i-Mannitol - kwingcinezelo eqhelekileyo nephakamileyo yokukhupha umthamo ogqithiseleyo kunye nezifo;
- U-Eufillin ngeDexamethasone - ukususwa kwe-bronchial spasm, njl.
I-edema ye-edema i-Quincke yonyango ihlukeneyo, ngamanye amaxesha iqhutyelwa ngokunyuswa kweplasma yegazi kunye nokusetyenziswa kwezi ziyobisi:
- I-z-aminocaproic acid;
- Counter.
Ngenxa yesigaba esichukumisayo, unyango luquka:
- ukukhutshwa kwezinto ezivakalayo;
- Izifundo ezimfutshane zonyango lwe-hormonal (Prednisolone, Dexazone);
- ukusetyenziswa kweziyobisi ukuqinisa inkqubo yeentlanzi kunye nokunciphisa ukunyaniseka kwe-vascular (Ascorutin, calcium, iivitamin complexes);
- ukuthatha i-antihistamines (i-Loratadine, i-Suprastin, i-Cetirizine).
Iziphumo ze-Quincke's Edema
Izigulane ezifunyaniswa ukuba zinama-angioedema aphindaphindiweyo zihlala zikulungele ukuphepha iingxaki kwaye zithwale izidakamizwa eziyimfuneko ukuyeka ukuhlaselwa. Xa kukho ukuvuvukala kweQuincke, iimpawu kunye nokunyangwa kwezinto ezinganyanzelwangayo okanye ukunganyanga okwenziwe unyango, oku kusongela impilo kunye nemiphumo ebungozi. Phakathi kwazo:
- tshutshisa i-anaphylactic;
- asphyxia;
- izifo zengqondo;
- cystitis;
- isithintelo esiswini;
- peritonitis.