Emzimbeni womfazi ngamnye, amabini ama-hormones eesini kunye namabhinqa (androgens) aveliswayo. Ngamanye kwezi zinto eziphilayo zilawula imisebenzi yokuzala, umsebenzi weenkqubo zangaphakathi. Ukwanda okanye ukuncipha kwiinkcenkceshelo zezi zinto kuchaphazela impilo kunye nokuphila ngokubanzi kwabasetyhini.
Androgens - Ziyiphi i-hormone kubafazi?
Amahomoni angamadoda emzimbeni wesibhakabhaka aveliswa ngama-ovari kunye nama-adrenal glands. Bayadlala indima ebalulekileyo kwinqanaba elifanelekileyo leenkqubo zokuxilisa umzimba. Phakathi kwemisebenzi ephambili yale mihla:
- ukwakheka kwamalungu omzimba;
- uphuhliso lweethambo;
- ukubunjwa kweempawu zesondo zesibini;
- ulawulo lwezenzo zesondo.
Ukuchithwa kwe-hormone ye-hormone kumzimba wesetyhini kukuphulaphula. Xa i-androgens kubasetyhini ingaphezu kwexesha eliqhelekileyo, oogqirha bakhuluma nge-hyperandrogenism, ngokunciphisa inani labo-malunga ne-hypoandrogenism. Kwindlela nganye yokukhubazeka ibonakaliswa yimpawu zayo kunye nomfanekiso wekliniki, ngoko ke kunokwenzeka ukuba lona wesifazane ngokwakhe ukukrokra ukuphambuka kwimiqathango, ngokuguqulwa okubukhali ekubonakala kwakhe.
Amahomoni angamadoda kumzimba womzimba-mabhinqa
Uphando oluqhutywe ngabafundi be-physiologists luye lwaqinisekisa ukuba emzimbeni wecala ngalinye elungileyo kukho iintlobo ezininzi ze-androgens kanye. Kule meko, i-hormone ye-hormone yamadoda oyintloko kubasetyhini egazini iqulethwe ngxininkulu enkulu xa kuthelekiswa namanye amaqumrhu e-biological ale qela. Egazini lentombazana kukho:
- androsterone;
- androstenedione;
- androstenediol;
- dihydrotestosterone.
Androgens - isiqhelo kubafazi
Ukuze kuchaneke ukuphulwa kweenkqubo ze-hormonal, oogqirha banika uhlalutyo lwamabhinqa eesini zesini kubasetyhini. Ukugxeka okunjalo ukuguquka ngokutshintsha okubonakalayo ekubonakalayo, ukufunyanwa kwezimpawu zomfazi. Xa kuqhutyelwa isifundo, isalathisi samahhala kunye ne-androgen isungulwe, echazwe njengepesenti. Ukugqitywa kwesi sikhombisi kuya kubonwa kwiinqanaba ezahlukeneyo zomjikelezo. I-Androgens kwabasetyhini emzimbeni atshintsha ukugxininisa kwizigaba zomjikelo:
- isigaba sokulandelelana sisi-0.8-9.3%;
- isigaba sokusasaza 1,3-17;
- isigaba esilandelayo ;
- ixesha lokuyeka umama - ukuya ku-6.6%.
Ngokwahlukileyo, ukuxinwa kwe testosterone yamahhala kubasetyhini kunokwenziwa. Xa uneminyaka yobudala, esi sibonakaliso sitshintsha ixabiso, kodwa akufanele lidlule le miqathango elandelayo:
- ukuya kwi-9 iminyaka-0,06-1,7 picogram / ml;
- 9-13 ubudala - 1.7;
- 13-18 - 4.1.
Amahomoni angamadoda ayichaphazela njani umfazi?
Impembelelo yokuba amahomoni angamadoda asebenzayo kumfazi angabelana ngokwahlukileyo (kubonakala kungekho ngaphandle kophando) kwaye afihliwe. Xa amahomoni angamadoda kumabhinqa emzimbeni aquletheke kakhulu, oku kungenziwa ngokuchithwa ngokutshintsha ukubonakala. Nangona kunjalo, impembelelo kwizitho zangaphakathi kunye neenkqubo ezenzeka kuzo azibonakali. Ngaphantsi kwezenzo ze-androgens kumzimba wesetyhini kwenzeka:
- ukwanda kwinqanaba le-enzyme ye-glycolytic;
- ukuphucula ukuveliswa kwamaprotheni;
- ukunciphisa umthamo wee-depositol;
- ukutshiswa kwamathambo angaphantsi;
- ukwanda kwezesondo.
I-androgen engaphezulu kweyabasetyhini
I-predominance yama-hormone wesilisa kubasetyhini kulula ukujonga ngokubonakala, umzimba. Ezi zigulane zinamahlombe athabileyo, umvuzo womntu, ilizwi eliphantsi. Izandla, amabele, ezinxibe ngeenwele, abanye abafazi baqala ukukhula emasipini kunye neendevu. Utshintsho kwi-concentration ye-androgens kwabasetyhini inokubangelwa kwizinto ezimbini:
- Ukwandiswa kwama-hormone emzimbeni - ukuveliswa kwemveliso ye-adrenal ye-adrenal excessively, ukwehla kwinqanaba leeprotheni ezibopha kunye ne-orrogens.
- Iziphazamiso ezifanelekileyo - i-hormone zenziwe ngobuninzi bomthamo, kodwa i-receptors ibonisa ububele obuninzi kubo.
Ukugqitha kwamahomoni angamadoda kubasetyhini - iimpawu
Iingqungquthela zokuqala zokunyuswa kwegazi kunye ne-androgens kufuneka zivelwe ngenguqu kwiinkqubo zesebe zangaphakathi. Abafazi abanjalo bayaqaphela:
- ukuphulwa kunye nokuphazamiseka komjikelezo wesini , izifo eziqhelekileyo zenkqubo yokuzala;
- ukwandisa i-insulini egazini;
- ukungabikho kwinqanaba le-ovulatory lomjikelezo.
Nangona kunjalo, kwiimeko ezininzi, i-androgens engaphezu kwama-womenrogs anempawu ezi zilandelayo ziyakwazi ukuchongwa kwiinguqu zangaphandle kumzimba:
- iziphene zokuzilungisa - i-acne, ukubukeka ubuso, ukunyuka kweenwele;
- ukwanda okwebukhulu bomzimba;
- ukwanda kwemveliso ye-sebum;
- utshintshe umbala wesigca.
Indlela yokunciphisa amahomoni emaduna emzimbeni wesetyhini?
Ngaphambi kokunciphisa i-androgens kwabasetyhini, oogqirha basungula isizathu esabangela ukwanda kwenkxalabo yabo. Kule meko, isiphelo senziwe ngokucacileyo, ngokusekelwe kwizigqibo zeengcali eziliqela kwangoko (umzinzi wegazi, i-endocrinologist, therapist, dermatologist). Inkqubo yonyango ikhethwe ngabanye, kwaye inkqubo ngokwayo ifanele igxile ngokupheleleyo. Ukutyunjwa kweziyobisi, umlinganiselo wabo, ubude kunye nobude bokusetyenziswa kwenza ugqirha. Phakathi kwezinto ezisetyenziselwa ukunciphisa i-androgens kubasetyhini asetyenziswayo:
- Metformin;
- Dexamethasone;
- UJanine;
- UDiane-35.
Ukungabikho kwe-androgens kwabasetyhini
Xa ama-hormone wesilisa abesifazana angabanamanani aneleyo, isondo esilungileyo asikwazi ukubona utshintsho lwangaphandle. Ngokungaqhelekanga, le ngxaki iboniswa ngokunyuka ngokukhawuleza kwinqanaba legazi le-cholesterol, elisungulwa ngokuhlalutya kwegazi. Kwixesha elide, ingxaki leyo ayikwazi ukuzibonakalisa, ngoko kudla ukufumaneka kwiimeko eziphezulu zeemodem.
Ukusilela kwe-androgens kuthintela impilo impilo yabasetyhini kunye nentlalo-ntle. Phakathi kwezifo ezihambelana nokungabikho kwamahomoni esilisa:
- ukukhulelwa kwegazi;
- osteoporosis;
- i-atherosclerosis.
I-Androgens kwabasetyhini iyancipha - iimpawu
Xa i-androgens iyancipha kubasetyhini, iimpawu ezibonakalisa le ngxaki azigcinanga ulinde. Amantombazana ayaqaphela ukunciphisa okunzulu kwisifiso sezesondo, inqabileyo yesini ayifuni ukuzonwabisa. Ngexesha elifanayo, uvakalelo lwengqondo engekhoyo, uhlala udibana. Phakathi kwezinye iimpawu ezibonisa ukuba i-androgens yabasetyhini iyancipha:
- ingqondo engapheliyo yokukhathala;
- utshintsho lweemvakalelo rhoqo;
- ukuhlukana kwamathambo.
Indlela yokwandisa izinga lamahomoni angamadoda kwabesetyhini?
Ukuqhelanisa ukugxininisa, ukwanda okanye ukunciphisa amahomoni angamadoda kubasetyhini, oogqirha baphatha unyango ngabanye. Kule meko, kuyimfuneko ukuqwalasela:
- ubunzima besifo;
- kwinqanaba leprogram yoluntu;
- ubukho bezifo ezidibeneyo.
Ekuqaleni, ukuzimela ngokwesiqhelo se-androgen, oogqirha bancomela izigulane:
- Shintsha indlela yobomi.
- Ukuqwalasela ulawulo lomhla (ukuphumla ebusuku ngaphandle kweeyure eziyi-8).
- Ukwahlula ukutya kwakho.
- Ukuyeka imikhwa emibi.
Ukuba amanyathelo athatyathwe azange alethe utshintsho, i-hormone therapy inqunywe. Isekelwe ekusetyenzisweni kwamalungiselelo e testosterone. Ukufumana unyango, ezi ziyobisi zingasetyenziswa
- Omnadren;
- Udidi;
- Testosterone propionate.