Ubude bee-IVF zezigaba kuxhomekeke kumalungiselelo asetyenziswayo ukuphumeza. Kukho ukungafani kwimihla emininzi ubude benkqubo emfutshane ye-IVF ye-pituitary blockade yi-agonists okanye abachasayo kwi-GnRH.
Ixesha elifutshane elilandelwayo le-IVF?
Umgaqo-mfutshane omfutshane kunye nokusetyenziswa kwe-GnRH i-agonists kufuneka ihlale iintsuku ezingama-28 ukuya kwi-5, kwaye i-ultrashort esebenziselwa abaphikisi be-GnRH ithatha iintsuku eziyi-25 ukuya ku-31.
Umgaqo-nkqubo omfutshane nexesha elide we-IVF isebenzisa izilungiso ezifanayo ze-hormone, kodwa isingeniso sawo asiqali kumjikelezo omnye wesinye, kodwa sithatha enye yangaphambili, eya kunika inani elikhulu leeqanda eliphezulu. Ukwenza oku, ukukhutshwa kwe-pituitary gland kuqala ngeveki ngaphambi komjikelo, xa izigaba eziphambili ze-IVF ziqala.
Amanqanaba e-IVF - imigaqo emfutshane
Iskimu somgaqo-nkqubo omfutshane we-IVF iqulethe izigaba ezine zokuphunyezwa kwayo:
- ukuvuselelwa kokugqithisa (inkqubo yokuvuselela i-ovulation kwiintlobo ezininzi ze-ovaries yamfazi);
- ukugqitywa kwee-ovane (ukukhupha i-follicle evuthiweyo ye-ovum yokuchumisa, imeko enyanzelekileyo - ekuhambeni kwexesha lokubambisa kuyimfuneko ukuyeka ukulala ngesini iintsuku ezi-3);
- ukuxubusha kwama-embrosi (emva kokugqithwa phantsi kwe-microscope, funda izinto eziphathekayo, ukhethe kwaye uququze amaqanda apheleleyo kwaye ubandakanye ama-embryos kwiinqununu ezininzi ze-zygotic, ukuya kwii-4 ukuya kwii-8 zeeseli);
- Ukufakelwa kombungu kwisisu (kunye nenkxaso enyanzelisayo yomsebenzi omzimba ophuzi kunye neprogesterone kunye nokulawula kokukhulelwa 2 iiveki emva kokumiselwa).
Inkqubo ye-IVF kwiintsuku
Ixesha le-IVF lixhomekeke kwiyiphi imigaqo esetyenziswayo-ixesha elide, elifutshane okanye elifutshane. Ngexesha elide, ngokwahlukileyo kwabanye, i-hormonal blockade ye-pituitary gland iqala ukusuka kwiintsuku ezingama-21 zomjikelezo wangaphambili, ifumana inani elikhulu lamaqanda, kodwa ukuphuhliswa kwengxaki, i- ovarian hyperstimulation syndrome, inokwenzeka.
Kwi-shortcut ne-ultrashort protocol, i-blockade ye-pituitary iqala ukususela kumhla wesi-2-5 wesigxina sokuya esikhathini kunye nokuvuselela ngokukodwa kwimizuzu engama-12 ukuya kwe-17 kwi-protocol emfutshane, kunye neentsuku eziyi-8 ukuya ku-12 kwi-ultrashort.
Ukugqithwa kwama-ovari kunye neprotocol emfutshane ye-IVF kwenziwa ngomhla we-14-20 ukususela ekuqaleni kokuvuselela, kunye ne-ultrashort iintsuku ezili-10 ukuya kwe-14 zokunyusa.
Ukufakelwa kombindi wezo zombini iiprotokthi zenziwa iintsuku ezingama-3-5 emva kokukhishwa kwe-ovarian, kunye nokulawula ukukhulelwa - iiveki ezimbini emva kokumiselwa, ngelixa zixhasana kunye nomsebenzi we-yellow body kunye nama-analogs e-progesterone.