I-Estradiol yi-hormone ye-steroid, eveliswa ikakhulukazi kuma-ovari kunye nesakhiwo esicacileyo se-adrenal gland kubafazi. I-Estradiol inoxanduva lokuphuhliswa ngokwesondo ngohlobo lwentlobokazi, ukwakheka kwengqondo kwabasetyhini. Isenzo sale hormone sijoliswe kwisibeleko, izilonda zentlungu, ama-ovari, ama-tublopian tubes.
Iqondo le-estradiol liqhelekileyo
Isiqhelo se-estradiol kubasetyhini siyahluka ngokuxhomekeka kwisigaba sokujikeleza kwimihla kwaye:
- 97.5 - 592 i-pmol / l - isiqhelo se-estradiol kwisigaba sopolisi;
- 685-1404 pmol / L yinto eqhelekileyo ye-estradiol kwi-preovulatory peak;
- 120 - 738 pmol / l - isiqhelo se-estradiol kwisiqendu sesigxina;
- 9 - 258 pmol / l - isiqhelo se-estradiol ekupheleni komntu.
I-Estradiol hormone kubantu
I-Estradiol ikhiqizwa emzimbeni wesilisa ngama-testes kunye nesakhiwo senethiwekhi se-adrenal glands. I-Estradiol kumadoda isebenzayo i-metabolism, kuquka ne-calcium. Ngokuqhelekileyo, izinga le hormone kumadoda li-19.7 - 242 ntol / l.
I-norm ye-estradiol ekukhulelweni
Xa ukhulelwe kwaye njengoko ikhula, izinga le-estradiol emzimbeni wowesifazane landa kakhulu. Eli nqanaba eliphezulu le hormone lifika ngaphambi kokuba kuthunyelwe, kwaye emva kokuhanjiswa, izinga le-estradiol liqhelekile.
I-Estradiol ngexesha lokukhulelwa liveliswa yi-placenta. Isenzo salo hormone sijoliswe kwisibeleko, iimpahla zayo, igazi le-coagulability. U-Estradiol ukhusela umntwana ozayo xa ekhulelwe. Umgangatho walo:
- 215.0 - 430.0 pg / ml kwi-trimester yokuqala;
- 800.0 - 576.0 pg / ml kwi-trimester yesibini;
- 1810 - 13,900 pg / ml kwi-trimester yesithathu.
Umgangatho wokuhlalutya kwinqanaba le-estradiol
Uhlalutyo kwinqanaba le-estradiol linikezelwa ukuxilongwa kwentsholongwane yomjikelezo wesini kunye nokungabikho komntwana. Kwiintsuku ezi-3 phambi kokunikezelwa kwesi vavanyo asikhuthazwa ngokuzilolonga umzimba. Uhlalutyo lunikwa kwisisu esingenanto.
Estradiol ngaphezu kwesiqhelo
Umgangatho we-estradiol ngaphezu kwesiqhelo ungabonwa ngezo pathologies:
- ukuphikelela kobugcisa;
- i-endometrioid cysts yama-ovari;
- i-tumor-secreting-tumor of ovaries;
- isrogenosecretizing testicular tumor;
- i-cirrhosis yesibindi.
I-Estradiol kumda ophantsi wesiqhelo
Iqondo le-hormone ye-estradiol lingancitshiswa ngu:
- Ukuzilolonga okunzulu kwabasetyhini abangaqeqeshiweyo;
- ukutshaya;
- u-hypogonadism;
- hyperprolactinemia;
- Ukungapheli kwemitha ye-hormone yesigaba esilandelayo;
- usongelo lokupheliswa kokukhulelwa kwe-genesis ye-endocrine.
Estradiol kwi-IVF
I-Estradiol inikeza ukukhula kwe-endometrium, ebalulekileyo xa ihamba inkqubo ye-IVF kunye nokudluliswa kombindi. Umgangatho we-estradiol emva kokudluliselwa kombindi kubonakaliso obalulekileyo bokukhulelwa okuphumelelayo. Umgangatho we-estradiol ulinganiswa ngosuku lokudluliselwa kwembungu kunye neveki kamva. Ngenqanaba elaneleyo le-estradiol, inkxaso yonyango ye-hormonal yomzimba inikezelwa, eqinisekisa ukuba uphuhliso oluphumelelayo lokukhulelwa.