Izidakamizwa ezichasene nezidakamizwa kwiimakethe zonyango zanamhlanje zihanjiswe kwiifom ezahlukeneyo-zombini kwiipowders, kunye nakwiipilisi, nakwiijovnyo, kwaye, kunjalo, ngendlela yamafutha kunye nama-gel. Enye ye-NSAID ezithandwa kakhulu kwi-gel ingabizwa ngokuthi iDiclofenac. Oku kubangelwe kwizinto eziliqela: okokuqala, isilwanyana asinayo intengo ephakamileyo, kwaye okwesibini, iyasebenza, kwaye, okwesithathu, ukuthandwa kwegama lonyango kusekelwa ezinye iifom - iinjongo ezifanayo kunye namacwecwe.
Ukubunjwa kwe-gel Diclofenac
I-Diclofenac imele imele i-agent ye-anti-inflammatory non-steroid kwaye iqukethe i-gel kwi-sodium ye-diclofenac.
Izinto ezincedisayo ezinceda i-gel ukuba ingene kumathishini kwaye zigcine iimpahla zazo ixesha elide zi:
- i-ethanol ilungiswe;
- propylene glycol;
- triethanolamine;
- i-carbomer;
- methyl lauryl hydroxybenzonate;
- ioli ye lavender;
- amanzi ahlambulukileyo.
Ukukhutshwa kwefom kunye nokuxilongwa kwe-gel Diclofenac
I-Gel Diclofenac iyatholakala kwiibhubhu ze-aluminium ezingama-50 no-40 g.
Ukongeza kwimiqulu, ukuxinwa kwezinto ezihlukileyo kuyahluka:
- I-Diclofenac i-gel 5% - nge-1 g yesisindo i-50 mg ye-diclofenac sodium;
- I-Diclofenac i-gel 3% - 1 g ye-gel i-30 mg ye-diclofenac sodium;
- I-Diclofenac i-gel 1% - i-1 g ye-gel ngu-10 mg yesithako esisebenzayo esisisiseko - i-diclofenac sodium.
I-Diclofenac ointment ayikho, kuphela i-gel iyatholakala.
Izakhiwo ze-Pharmacological zeGel Diclofenac
I-Diclofenac iyisisombululo esinemiphumo ye-analgesic, kunye neemeko ezichasayo ezichasayo. Inqanda i-enzyme i-COX-2 ne-COX-1, kwaye iphazamisa ukuhlanganiswa kwe-arachidonic acid kunye ne-metabolism ye-prostaglandines, eyenza inkqubo yokuvuvukala. Ngaloo ndlela, i-gel igxininisa ukusasazeka kokuvuvukala, kwaye ikhusela nokuphuhliswa kwayo kwimizimba ejikelezileyo.
Ngenxa yezi mpawu, i-Diclofenac isetyenziswe njengesigxina xa ukuvuvukala kubangelwa ukuvuvukala. Kuye kwanyelwe ukuba i-syndromes ibuhlungu njengendawo yokuhlaziywa kweengingqi xa ubuhlungu bubangelwa inkqubo yokuvuvukala.
I-Diclofenac iyanciphisa ukuvuvukala kwimimandla yokuvuvukala ngokubambisana, ukunciphisa ukuqina. Kwakhona kwiindawo zokuvuvukala, unokuphelisa intlungu, okanye iyanciphise kakhulu.
I-Diclofenac i-gel imiyalelo
Imiyalelo yokusetyenziswa kweGel ye-Diclofenac i-5%, kunye ne-3% kunye ne-1% ayifani. Umahluko uhlala kwiinkcenkceshelo zezinto ezisetyenziswayo, kwaye injongo yalo kuxhomekeke ekuqinikeni kweempawu. Ngokomzekelo, i-Diclofenac gel ne-concentration ye-5% isetyenziselwa ukuphatha intlungu ebuhlungu kwi- rheumatism .
Iimpawu zokusetyenziswa kwe-gel Diclofenac
I-Diclofenac imiselwe ezi zifo zilandelayo:
- i-rheumatic pathologies - bursitis , tendovaginitis, njl.;
- Iintlungu zesisu ezisemva kwe-rheumatism okanye umonakalo kwiisisu zomzimba;
- ukuvuvukala kwe-posttraumatic yamalungu.
I-giclofenac igel isetyenziswe ngaphandle, kunye nenani lento esisetyenziswayo esisodwa kuxhomekeke kubukhulu beendawo ezibuhlungu.
Nangona kunjalo, kukho iingcebiso ngokubanzi malunga nokusetyenziswa kwegelisi yeengcamango ezahlukeneyo:
- I-Diclofenac i-gel 1% - ukusebenzisa enye - ukuya kwi-4 g;
- I-Diclofenac i-gel 3% - isetyenziswa esinye - ukuya kwi-3 g;
- I-giclofenac i-gel 5% - ukusebenzisa enye ukuya kwi-2 g.
Abantwana abaneminyaka engama-12 ubudala kunye nabantu abadala bakhuthazwa ukuba basebenzise i-gel 3-4 ngamaxesha ngokunyakaza okukhanyayo.
Ukungqinelana nokusetyenziswa kweGel Diclofenac
I-Diclofenac ayikwazi ukusetyenziswa kwezi meko zilandelayo:
- ukukhulelwa (isincomo 3 trimester);
- lactation;
- abantwana beminyaka (ukuya kwiminyaka eyi-6);
- amanxeba, ukutshisa;
- ukusabela okubangelwa ngumzimba okanye isifo se-asthma esibangelwa ukusetyenziswa kwezilwanyana ezingekho-steroidal ezichasayo.
Ukuba kukho ukuphazamiseka kwegazi, i-Diclofenac Gel 5% kufuneka isetyenziswe ngokuqaphela.