Uvavanyo lwegazi lwe-hormone ye-thyroid lunokumiselwa oogqirha bezobugcisa ezahlukeneyo kwaye okwangoku iyanconywa rhoqo kwiimvavanyo ze-hormone. Olu phofu lufanelekile kwisiqingatha sesibalo sabantu, apho izifo ze-thyroid zihlala ziphindwe kabini ngaphezu kwesilisa. Makhe siqwalasele ngokubanzi, kuba yiyiphi i-hormones ye-TTG kunye ne-T4 enoxanduva, ukuba yeyiphi ixabiso eliqhelekileyo, kwaye lingayichaza ukuphambuka.
I-hormone yemveliso
I-thyroid gland iyilungu lenkqubo ye-endocrine, edlala indima ephambili ekulawuleni iinkqubo ezibalulekileyo emzimbeni womntu. Iqukethe izicubu ezixhambileyo ezibethelwa ngamagulane, igazi kunye neempahla zelfini. I-Shchitovidka iqulethe iiseli ezikhethekileyo - i-yourreocytes, ezivelisa i-hormone ye-thyroid. Amahomoni amakhulu e-thyroid gland yi-T3 (triiodothyronine) kunye ne-T4 (tetraiodothyronine), iqukethe iodine kwaye ihlanganiswa kwiindawo ezahlukileyo.
I-synthetic ye-hormone ye-thyroid ibangelwa kukuphuhlisa enye i-hormone-TSH (thyrotropin). I-TTG iveliswa ngamaseli e-hypothalamus xa ifumana isignali, ngaloo ndlela ikhuthaza umsebenzi we-thyroid gland kunye nokwandisa imveliso ye-hormone ye-thyroid. Iinkqubo ezinjalo eziyinkimbinkimbi zifunekayo ukuze igazi lenzeke ngokugqithiseleyo njengama-hormone e-thyroid asebenzayo, njengoko kufunekayo umzimba ngexesha elinye.
Imimiselo yehomoni ye-thyroid i-TTG kunye ne-T4 (inkululeko, jikelele)
Iqondo le-hormone ye-TTG inokuxelela inzululwazi malunga nemeko jikelele ye-thyroid gland. Isiqhelo ngu-0.4-4.0 mU / L, kodwa kufuneka kuphawulwe ukuba kwezinye iirabhoratri, kuxhomekeke kwindlela yokuhlola esetyenzisiweyo, umda oqhelekileyo unokuhluka. Ukuba i-TSH iphezulu kunexabiso lentengo, ithetha ukuba umzimba awunayo i-hormone ye-thyroid-stimulating (TTG iphendula ngoku kuqala). Ngexesha elifanayo, utshintsho kwi-TSH aluxhomekeke ekusebenziseni i-thyroid gland kuphela, kodwa nangokusebenza kwengqondo.
Abantu abaphilileyo, i-hormone ye-thyroid-stimulation hormone iguquka kwiiyure ezingama-24, kwaye umlinganiselo omkhulu kwigazi unokufunyanwa ekuseni. Ukuba i-TTG iphezulu kuneyona evamile, ithetha ukuba:
- ukugula kwengqondo;
- iingxaki ekusebenziseni i-adrenal gland;
- ukunyanzelisa umzimba;
- khulelwa;
- hypothyroidism;
- ukungabikho kwe gallbladder;
- gestosis enkulu, njl
Isixa esaneleyo se-TSH sinokubonisa:
- thyrotoxicosis;
- Ukunciphisa umsebenzi we-pituitary gland;
- izicubu zeengqondo;
- imfundo yobunzima kwi-thyroid gland, njl.
I-hormone ye-thyroid ye-T4 yabasetyhini:
- ekhululekile (engahambelani neeprotheni zegazi) 0.8-1.9 ng / dl;
- iyonke 4.5-12.5 μg / dl.
Icandelo le-T4 lihlala lihlala lihlala lihlala lilonke ubomi. Iziphumo eziphezulu zigcinwa kusasa nakwiindwendwe-ebusika. Isixa se-T4 sisonke sinyuka ngokuthwala umntwana (ngokukodwa kwi-trimester yesithathu), ngelixa i-hormone yamahhala ingancitshiswa.
Iimbangela zesifo sokunyuka kwe-hormone T4 ingaba:
- ukunyanya;
- goiter ;
- iinkqubo zokuvuvukala kwimizimba ye-thyroid;
- Usulelo lweHIV;
- isifo esibuhlungu besisu, njl.
Ukunciphisa inani le-hormone ye-thyroid i-T4 lidla ngokubonisa ukuba lunjalo lwezifo:
- ukusilela kwe-iodine emzimbeni;
- i-thyroiditis ;
- ukuphazamiseka kwe-hypothalamus;
- iifowuni kwi-thyroid gland, njl.