Kuza kube yimhla, i-gentamicin injecting ibonwa njenge-antibiotics eqinile kwintsebenzo ebanzi. Ukungena ngaphakathi kweeseli zebhaktheriya kwi-membrane, i-gentamicin iyaphazamisa ngokucacileyo ukusetyenziswa kweprotheni ye-pathogen. Ukusebenza ngokuphambene nePseudomonas aeruginosa, i-gram-negative baccia kunye ne-Gram-positive cocci, kubandakanyeka nalawo awamanye amayeza e-antibiotics.
Ukukhutshwa kwefom kunye nokubunjwa kweGentamycin
Isilwanyana sifumaneka ngefomati, ihla, i-powder yokulungiselela isisombululo sejoyi, i-liquid for injections (gentamycin sulfate). Ukubunjwa kwelokugqibela, ngaphezu kwezinto eziphambili, kubandakanya:
- metabisulfite sodium;
- hydroxyde
- i-sulfuric acid;
- ityuwa yesodium.
Imiqondiso yokusetyenziswa kweGentamycin
Isiza seGentamicin, esetyenziswa rhoqo kwizifo ezikhuselekileyo. Kusebenza ekwenzeni izigulane ezinomzimba ongaphantsi, owuphawu lwezigulane zesifo sikashukela, i-leukemia, njl.
I-Parenteral Gentamicin isetyenziswe kunyango lwe:
- izifo ezithathelwanayo zamathambo kunye namathambo, isikhumba (kubandakanya ukutshisa okukhulu kunye neqabunga );
- izifo zokuphefumula nezigqeba ze-ENT;
- ukuvuvukala okukhulu kwindlela yomchamo kunye nesisu esiswini;
- ukusuleleka kwinkqubo yesantya ephakathi.
Iinjongo ze-Gnatamycin zivame ukusetyenziswa kwizinyathelo zomzimba. Kwiinkqubo ezivuthayo kwiintlobo zabasetyhini, ichiza lilawulwa ngokulandelelana. Ndiyabulela ekusebenziseni i-antibiotiki, kunokwenzeka ukukhusela iingxaki ezinzima zentsholongwane, kuquka ukungabikho komntwana .
Imiyalelo yokusetyenziswa kwe-Gentamicin kuma-ampoules
Isiza seGentamicin sinokulawulwa kumzimba wesigulane ngokubambisene kunye nangenqindi. Ukusetyenziswa kwe-intravenous, isisombululo esisodwa seyeza sihlanjululwa kunye ne-50-100 ml yesisombululo se-chloride okanye isixa esifanayo nesisombululo se-5% se-glucose. Imiyalelo ithi i-dose yemihla ngemihla ye-Gentamicin kwi-injection yabantu abadala i-3 ukuya kwi-5 mg nganye nge-1 kg yesisindo somzimba, kuba abantwana abaneminyaka engaphezu kwe-14 yobudala, ibe yi-0.8 ukuya kwi-1.2 mg nganye ngekhilomitha yesisindo somzimba, ngeli nani lihlukaniswe libe li-2 ukuya kwe-4. . Inkqubo yokonyango iintsuku ezi-7 ukuya kwi-10. Ugqirha oya kungenza uhlengahlengiso olusekelwe kwisibandezelo sesifo, iminyaka yesigulane, njalo njalo. Ukwazisa kwakhona ixesha lekhosi yokwelapha, apho, ngokubhekiselele kwiimeko ezinzima, zinokuhlala zide.
Ukungqinelana kunye nemiphumo emibi yeenjini zeGentamycin
Ukusetyenziswa kweGentamicin akuvumelekanga:
- kunye novelwano olwandisiweyo lwesigulane kwii-antibiotics zeqela le-aminoglycoside;
- ukuphulwa komsebenzi weentso;
- i-neuritis yentsholongwane yokuhlola;
- ngexesha lokukhulelwa kunye nokuhlaselwa.
Xa unyango lweGentamicin, iziganeko ezimbi zilandelayo zingenzeka:
- isicupunu, ukuhlanza;
- intloko;
- buthathaka;
- zixhala;
- isikhumba sempembelelo;
- iingxaki zokuphicotha;
- ukulahleka kwengqiqo.
Isilwanyana sinakho ukuhluma, ngoko ke, ngeengxaki zentsholongwane, izilonda zengwenya zidlalwa.
Kwezinye iimeko i-Gentamicin inetyhefu kumzimba wesigulane. Kuye kwaphawula umphumo osisiphumo seziyobisi ekuphelelweni kwemizwa ehambelana nokusebenza kwezixhobo zentetho kunye ne-vestibular. Ngolu hlobo, isigulane kufuneka sibe phantsi kolawulo logqirha, ingakumbi xa i-dose ephezulu yonyango imiselwe okanye ikhosi yonyango iyaqhubeka. I-Gentamicin ayinqunywe ngokudibanisa ne-antibiotics enefuthe le-nephro- or ototoxic. Kwaye nangona kungekho nkcukacha echanekileyo ekusebenzisaneni kwe-gentamicin kunye neenyosi zotyphuzo, iingcali zicetyiswa kakhulu ukuba ziphephe ukusela ngexesha lonyango lonke.