I-alkaline phosphatase yiprothini enika inkqubo eqhelekileyo yokuphendula kwamakhemikhali amaninzi emzimbeni. Ukuphambuka kwesalathisi ukusuka kwinto eqhelekileyo kubonisa ukuba uphuhliso lwezilwanyana ezithile ezinxulumene nokuphulwa kwe-phosphorus-calcium metabolism.
I-almine phosphatase egazini
Ukuchonga ukuba umxholo we-alkaline phosphatase uchanekile okanye uguquka ukusuka kumgangatho oqhelekileyo, uvavanyo lwegazi lwe-biochemical lwenziwa. Kufuneka kuqatshelwe ukuba umgangatho we-alkaline phosphatase unxulumene nobudala, isondo, kwaye kwezinye iimeko imeko yomzimba wesigulane. Ngaloo ndlela, kubantwana aba balinganiswe ngokuphindwe kathathu kunabantu abadala, kwaye kwabasetyhini, izinga le-alkaline phosphatase egazini liphantsi kunabantu.
Ukongezelela, kufuneka kuqatshelwe ukuba iiparitha zezinga le-alkaline phosphatase zixhomekeke kwiimpawu ezisetyenziswayo ekuhlolweni kwegazi. Sinika iikholeji ezilinganisiweyo.
Iimpawu zegazi APF ekuhlalutyweni kwezinto eziphilayo (indlela yokuhlala rhoqo):
- kubantwana nakwi-adolescents - 1,2-6,3 mcd / l;
- kumadoda - 0,9-2,3 mkat / l;
- umgangatho we-alkaline phosphatase kwabasetyhini ngu-0,7-2,1 mc / l.
Isiqhelo sokugcinwa kwabantwana be-enzyme egazini legazi:
- ukususela ekuzaleni ukuya kwi-1 ngonyaka - ii-245-255 iiyunithi / l;
- ukususela kwiminyaka 1 ukuya kwi-9 iminyaka-ii-345-355 iiyunithi / l;
- ukusuka kwi-9 ukuya kwe-15 iminyaka-ii-275-285 iiyunithi / l;
- ukususela kwi-15 ukuya kwe-18 iminyaka-145-155 iiyunithi / ilitha.
Ukwanda okwenyuka kwinqanaba le-AF eliphakathi kwabantwana abangaphantsi kweminyaka engama-9 alilona lentsholongwane kwaye lidibaniswa nokukhula okukhulu kwethambo.
Kubantu, umxholo weenzyme zeli qela liqhelekileyo:
- ukususela kwiminyaka eyi-18 ukuya kwe-45 - iiyunithi eziyi-100-120 / ilitha;
- ukususela kwiminyaka eyi-45 ukuya kweyama-70 - iiyunithi ezili-120-145 iiyunithi;
- emva kweminyaka engama-70 - ii-180-190 iiyunithi / ilitha.
Isiqhelo se-alkaline phosphatase kwi-plasma yegazi kwabasetyhini (ngobudala):
- ukususela kwiminyaka eyi-19 ukuya kwe-45-iiyunithi ezingama-80-100. / l;
- ukususela kwiminyaka engama-45 ukuya kwengu-55 - iiyunithi ezili-105-115 / l;
- ukususela kwiminyaka engama-55 ukuya kuma-70 - iiyunithi eziyi-125-135 / l;
- emva kweminyaka engama-70 - iiyunithi eziyi-155-165 / ilitha.
Kuqhelekile ukuba utshintshe izinga le-enzyme ngexesha lokukhulelwa. Oku kubangelwa ukwakheka kwepenteka emzimbeni womama ozayo.
Izizathu ezinzulu zeziphumo zenguqu kwi-alkaline phosphatase
Kanye kunye nokuhlalutya kwamatye kunye nokufundiswa kwezinto, ukufunyanwa kwamanqanaba e-alkaline phosphatase kubaluleke kakhulu ekufumaneni izifo ezithile. Uhlalutyo lwezinto eziphilayo lukwabelwa izigulane ezinezilwanyana zesifo se-endocrine, i-digestive tract, isibindi, iintso. Ngokuqinisekileyo oku kuqhutyelwa ngabafazi abakhulelweyo kunye nezigulane ezilungiselelwe ukuhlinzwa.
Ngenxa yomonakalo kwizicubu zelungu okanye inkqubo, izinga le-alkaline phosphatase litshintsha. Ncedisa kwesi sifo:
- isibindi (i-cirrhosis, i-viral hepatitis, i- jaundice yomatshini );
- ducts;
- amathambo amathambo (i-rickets, i-osteogenic sarcoma, i-osteomalacia, njl.);
- izihlamba ezibi;
- i-rheumatoid arthritis;
- i-myocardial infarction;
- ukungaphumeleli komzimba;
- Ukhuhlane lwezilonda kunye nezifo zamathumbu ezihamba emathunjini ezihambisane nohudo;
- iingxaki ze-thyroid.
Imigaqo yokuhlalutya i-biochemical
Ukufumana idatha echanekileyo, kufuneka ulandele le mithetho elandelayo:
- Usuku olungaphambi kokuba uhlalutyo luvunyelwe ukuba luhlanganyele emsebenzini omzimba okanye kwizemidlalo.
- Akungaphantsi kweeyure ezingama-24 kunconywa ukuba ungaphuzi utywala kwaye ungasebenzisi imilu ebangela ukuba utshintsho kwizinga le-alkaline phosphatase.
- Uhlalutyo lwenziwe kwisisu esingenalutho ekuseni.
- Isampululelo segazi ukusuka emthanjeni ukuhlalutya kwenziwa kwimiqulu ye-5-10 ml.
Ukongeza, ukwenzela ukuba kucaciswe ukuxilongwa, umchamo, iifesi, ijusi yamathumbu angabelwa, kwaye i-hepatic, intestinal, ithambo, i-placental, i-isoenzymes ye-alkaline phosphatase inokumiselwa.