Igazi lomntu liqukethe inani elikhulu lezinto ezahlukeneyo. Ndiyabulela ngamnye kubo, umzimba ukwazi ukusebenza ngokuqhelekileyo. Elinye lala maqumrhu yi-hemoglobin ye-glycosylated okanye i-HbA1C, eyona nto ingabalulekanga kubafazi kunye namadoda. Le nkunkuma yinxalenye encinci yeprotheni yendabuko. Ukwahluke kwaso kwi-hemoglobin eqhelekileyo-ngokubambisana ne-molecule ye-glucose.
Isiqhelo se-glycosylated hemoglobin egazini
Inyaniso yokuba i-HbA1C iqulethwe kwigazi yinto eqhelekileyo. Ngamanani amancinci eli qela lingabakho emzimbeni walo nawuphi na umntu. Nangona ubukho be-hemoglobin ye-glycosylated bubhekwa njengobonakaliso bokwenene besifo sikashukela, kunokwenzeka ukuba kuqinisekiswe i-A1C - enye yegama elingezinye i-compound-nakwigazi labantu abangabikho kwisifo.
Iingcali zenze iirhafu ezikhethekileyo ze-hemoglobin HbA1C, zilinganiswe ngeepesenti. Zibukeka ngathi:
- Ukuba inani loxhumo aludluli kwi-5.7%, ngoko akukho zizathu zokukhathazeka. Ngeli nqanaba le-A1C, i-carbohydrates metabolism iyinto eqhelekileyo, kwaye ngoko ingozi yokufumana isifo sikashukela iyancinci.
- Nge-hemoglobin ye-glycosylated, ukusuka kwi-5.7 ukuya kwi-6 yeepesenti, isifo sikashukela asikabi. Nangona kunjalo, xa kunjalo, ukutya okunzulu kunye nomxholo we-carbohydrate ophantsi kufuneka uhambe. Oku kuyaqinisekileyo ukunceda ukukhusela isifo sikashukela.
- Ngokwezimiselo, kwinqanaba le-hemoglobin ye-glycosylated ukusuka kwi-6.1 ukuya kuma-6.4 ekhulwini, umngcipheko wokugula unyuke ukuya phezulu. Ukufumana iziphumo ezinjalo zokuvavanya, ukuphila ngendlela enempilo kunye nesondlo ukuhamba oku kwangoku, ngaphandle kokucinga.
- Ukuba inani le-HbA1C lingaphezulu kwezinga le-6.5%, oogqirha bafumana ngokukhawuleza ukuba "isifo sikashukela". Emva koko, iimviwo ezongezelelweyo zenziwa, kodwa kwiimeko ezininzi ukuxilongwa kuqinisekiswa.
- Xa uhlalutyo lubonisa izinga
i-hemoglobin ye-glycosylated ngaphezu kwe-7%, akukho nto iqinisekile yokuba isigulane sinohlobo lwesifo sikashukela.
Ukuba i-hemoglobin ye-glycosylated ingezantsi
Kwakhona kwenzeka ukuba iziphumo zophando zibonisa ubungakanani obaneleyo be-hemoglobin ene-glucose. Isixa se-A1C egazini sinokunyuka ngokukhawuleza emva kokusebenza kakubi kunye nokumpontshelwa igazi. Ukunciphisa izinga leprotheni linokuthi:
- i-hypoglycemia;
- ukukhulelwa kwegazi ;
- ukuphuma kwegazi.