I-Metronidazole - iipilisi, ezineempembelelo ze-antimicrobial kunye ne-antiprotozoal. Impembelelo yale mpendulo isekelwe kwinto yokuba i-nitro iqela lesilwanyana lifaka umxube wokuphefumula we-protozoa kunye ne-anaerobes, ngenxa yoko iinkqubo zokuphefumula ziphazamiseka kwii-microorganisms kunye neeseli ze-pathogenic ziyafa.
Imiqondiso yokusetyenziswa kwamacwecwe e-Metronidazole
Izimpawu zokusetyenziswa kwamacwecwe e-Metronidazole ziyi-protozoinfections. Ngosizo lwabo unako ukunyanga:
- emathunzini amebiasis ;
- giardiasis;
- leishmaniasis;
- i-amebiasis eyongeziweyo;
- Trichomonas vaginitis;
- trichomoniasis;
- balantidiasis.
Ukusetyenziswa kwamacwecwe e-Metronidazole kuboniswa kwizifo ezibangelwa yi-anaerobic bactteria. Ezi zi:
- izifo zesisu (umzekelo, i-peritonitis okanye i-abscess yesibindi);
- izifo zeengcambu zeplavic;
- ukunqandwa kwamabhaktheriya kwamalungu, amathambo kunye nenkqubo yesifo.
Ukufunyanwa kwesi sidakamizwa kucetyiswa ukuba:
- pneumonia;
- ukuxhamla;
- ukungabikho kwemiphunga;
- sepsis;
- endocarditis yebhakteria.
I-Metronidazole kwiipilisi isetyenziswa nakwiimeko ezilandelayo:
- i-colitis ;
- utywala obunaphakade;
- isilonda sesilonda;
- ukuthintela iingxaki zokuhamba emva kokusebenza.
I-Metronidazole ye-thrush
I-Metronidazole yi-antibacterial agent. Kodwa ezi macwecwe ziphelisa umphumo wezinye iintlobo zefungi:
- Candida Pseudotropicalis;
- Candida;
- Candida lusitaniae.
Yingakho iipilisi ze-Metronidazole zihlala zichongiwe ukuba zitshathwe. Kodwa kwi-fungi yentsapho ye-Candida (izifo zentsholongwane yesimvu) le nkunkuma ayikwazi ukuba nefuthe elifanelekileyo, ngoko isetyenziselwa kuphela uhlobo oludibeneyo lwesifo kubafazi. Ulwaphulo kufuneka lubandakanye ama-antibiotics, amayeza antifungal kunye neziyobisi ezibanzi. Kwimeko nganye, i-dosage ikhethwe ngabanye, ekubeni kwindlela enzima ye-milkwoman, i-Metronidazole kufuneka ikhusele izifo ezahlukahlukeneyo kunye nezicathulo.
Indlela yokusetyenziswa kweMetronidazole
Ngaphambi kokuba uthathe amacwecwe e-Metronidazole, kufuneka ufumane iimvavanyo zelabhoratri uze uthintane nogqirha ukuqinisekisa ukuba ukuxilongwa kuchanekile. Oku kuyimfuneko, kuba umlinganiselo weli ziza lixhomekeke kwisifo.
I-Metronidazole ikwandisa umphumo we-antiticoagulants engqalileyo kwaye ibangela ukunganyameki kwi-ethanol. Ayinakusetyenziswa kwonyango nge-disulfiram, njengoko oku kunokukhokelela ekubonakaleni kwempawu zegazi. Ngenxa yengozi enkulu yemiphumo emibi, i-Metronidazole ingasetyenziselwa kwiipilisi kuphela emva kokuba isiguli sigxothwe ekuthatheni i-cimetidine, amalungiselelo e-lithium kunye nama-agent agqugquzela i-enzymes ye-oxidation ye-microsomal. Ukuba isiguli sisoloko sinezondlo, i-ataxia kunye nokunyuka kobuchopho be-neurological, unyango kunye nalo mayeza kufuneka lubekwe.
Ukungqinelana kunye nemiphumo emibi yeMetronidazole
Ungasebenzisi iipilisi zeMeterronidazole ngovelwano kwizinto ezenza iziyobisi. Kwakhona, ukuwamkela kwabo kuyaphikisana xa:
- leukopenia;
- izilonda zomzimba zesimiso senzwa;
- ngexesha lokutya;
- ukungaphumeleli kwintambo (ifomu elibi);
- khulelwa.
Ukuba udlula umlinganiselo wee-tablet ze-Metronidazole, iziphumo ezibi zingenzeka:
- isicefe
- ukuhlanza;
- inkcenkceshe;
- stomatitis;
- intloko;
- i syncopal ithi;
- ukucaphuka;
- buthathaka;
- izifo zokulala;
- neuropathy;
- ezahlukeneyo iziphumo.
Xa kufakwa ixesha elide, le nkunkuma ingakhokelela ekubeni uvavanyo lukaNelson lwaluyinyaniso kwaye ludle umchamo kumbala omnyama.