Isifo sikaM Werlhof

Isifo sikaM Werlhof - i-thrombocytopenic purpura - isifo esibonakaliswe ngempembelelo enobungozi ngenxa yemvelaphi ye-aggregation aggregation (gluing) yamaplatelet. I-micromrombi eyenziwe yifake iimbane zeetriyiti ezincinci. Ukongezelela, kukho ukuchithwa kweeseli zegazi kunye nokuncipha kwinani leeplatelet.

Izizathu zeengxaki zikaM Werlhof

Okwangoku, izizathu ezibalulekileyo ze-thrombocytopenic purpura aziwa. Ukwabela iifom zasePrayims kunye nezesekondari zesifo. Iifom zaseprayimari zifa ngokwemvelo okanye zibonakaliswe ngenxa yesifo esithathelwanayo. Iifom zesiSeshini zinemiqondiso yesibalo sezifo.

Izibonakaliso zezifo zikaVerlhof

Esi sifo siqala ngokuqinileyo, ngenxa yesizathu esicacileyo, ngamanye amaxesha ngokumalunga nemvelaphi yesifo sesisu okanye i-ARI. Kwisigulane kwisigaba sokuqala, iimpawu ezilandelayo zibonakaliswa:

• umkhuhlane;
• isicupunu (ukuhlanza okunokwenzeka);
• intloko;
• ubuthathaka jikelele, ukukhathala;
• intlungu kwisifuba nesisu.

Uphawu oluphambili luyi-bruises kunye neengqumbo ezingaphantsi, ezichaza igama lesibili le-purpura yesifo-thrombocytopenic purpura.

Emva kwexesha elifutshane, i-symmatic syndrome ibonakala ngokukodwa ngendlela:

• ukuphuma kwamanzi, isisu, kunye neyabasetyhini kunye nesisu;
• ukuphuma kwegazi , iimbumba zomzimba;
• ukubola kwi-retina yelihlo;
• hemoptysis.

Ukubonakaliswa kweempawu zihamba kunye neengxaki zegazi, ezifana ne:

• ukulibala;
• kulala;
• ukuphazamiseka kwithuba kunye nexesha;
• Umbono wehla
• ukukhubazeka kwamanye amazwe.

Kwiimeko ezinzima, kunokwenzeka ukuhlakulela i-coma.

Ukuhlaziywa phantsi kwesikhumba kuya kubanzi kwaye kunendawo enkulu. Ngokuxhomekeka kwimiyalelo yesigqirha, i-effusions inombala obomvu obomvu obunobumba (njengento eyisikruba esidala).

Ukuxilongwa kwesifo sikaVerf kuqala ngokuhlolwa kwesigulane kunye ne-amnesis. Inkathazo yokuxilonga iquka ezi zilandelayo:

1. Ukuhlalutya ngokubanzi kwegazi (OAK). Esi sifo sinqunywe ngokunciphisa izinga le-erythrocytes kunye ne-hemoglobin, ukunciphisa inani leeplatelet kunye nokufumana i-antiplatelet antibodies.
2. I-sternary puncture - ukuthatha umongo wethambo ukuze uviwo lube ngumbono we-sternum puncture. Kuhlolisiso lwe-cell composition, ukwanda kwenani lamakaryocytes, inani elincinci lamaplatelets, zifunyenwe, ngelixa kungekho zinguqulelo kumnxeba wethambo, umzekelo, ezo ziphawu lohlobo lwe-tumor.
3. I-Trepanobiopsy - isifundo somongo wethambo kunye ne-periosteum kunye neethambo (ukusuka kwingingqi ye-pelvic), ithathwe ngoncedo lwecebo lonyango lwe-trephine. Ngesi sifo sikaVerlhof, umlinganiselo we-fatty and hematopoietic bone marrow uhambelana nokuqhelekileyo.

Ukunyangwa kwezifo zikaVerlhof

Amanyathelo okunyanga axhomekeke kwimeko yesifo. Unyango luyenziwa ngenye yeendlela ezilandelayo:

1. Ukusetyenziswa kwe-corticosteroids ngenjongo yokubamba isifo segazi kunye nokwandisa izinga leeplatelet egazini. I-Prednisoni imiselwe kwisilinganiso se-1 mg nge-1 kg yesisindo somzimba ngosuku. Xa kukho inkalo ebalulekileyo yesifo, idosi iphindwe kabini.
2. Ukuba isiphumo esifanelekileyo asizange siphumelele, isiguli sinconywa ukususa ipeni . Ngokwezibalo zonyango, kwi-80% yezigulane emva kokungenelela kokuphazamiseka kugqityiwe.
3. Kwiimeko ezinqabileyo, emva kwe-spleen splenectomy, ukudlula kwegazi, kwaye isifo sifuma, i-immunosuppressants imiselwe (Azathioprine, Vincristine) kunye ne-glucocosteroids.

Ukususa iimpawu zangaphandle zesifo segazi, ama-haemostatic asetyenziswa:

• Adroxon;
• Ukutya;
• Siponti yeHemostatic;
• estrogens.