Pradaxa liyilisi elineqela le-anticoagulant and antithrombotic drugs. Ziyisebenzisa kwimathambo kunye ne-traumatology kwithuba elide emva kokubambisa ngokubanzi ukukhusela i-thromboembolism ye-venous.
Ukukwazi ukusebenzisa iPradax
Isisombululo esisisiseko salo mfuziselo ngu-dabigatran etexilate. Ngenxa yolu hlobo, umsebenzi we-thrombin ukhutshwe emva kokufaka isicelo sePradax. I-Dabigatran etexilate ixutywa ngokukhawuleza kwaye iguqulelwe ibe yi-dabigatran (i-inhibitor ephendulelwe ngqo) ngexesha le-hydrolysis. Ukuphumelela kwesilwanyana kuncitshiswe ngu-20% ukuba ubunzima bomntu bukhulu kune-120 kg, kwaye banda ngo-25% ngesisindo somzimba wesigulane esingaphantsi kwama-48 kg.
Iimpawu zokusetyenziswa kwe Pradax zi:
- ukukhusela i-thromboembolism ye-venous;
- ukuthintela iintlobo ezahlukeneyo ze- thromboembolism ;
- ukuthintela isifo senhliziyo kwizigulane ezinefayibrillation.
Ukusetyenziswa kwe-Pradax kuboniswa ngokuqhelekileyo kuzo zonke izigulane ezinokuxilongwa emva kokusebenza kwamathambo, ukususela kuzo zonke ii-coagulants zanamhlanje le nkunkuma ithathwa njengolusebenzayo. Kwakhona, eli lonyango limiselwe emva kokudityaniswa kwamadolo endoprosthetics. Ukufumana ukufumana ngokukhawuleza komzimba kufuneka uqalise iiyure ezine emva kokuphela komsebenzi.
Ukungqinelana nokusetyenziswa kwePraxixi
Nangona unezibonakaliso zokusetyenziswa kwamachiza kaPradax, awukwazi ukuyisebenzisa ekwenzeni unyango lwe-hypersensitivity kunoma yiyiphi inxalenye yesilwanyana. Ungaqali ukuthabatha iyeza kunye nesimo esinzima sokuphelelwa kweengso, ukuphazamiseka ngokukhawuleza okanye ukuphazamiseka kwe-homeostasis kunye nokuphuma kwegazi ngokukodwa.
Ukungqinelana nokusetyenziswa kwe Pradax nako:
- umsebenzi wesibindi;
- intlungu yomgudu kunye nengqondo;
- neoplasms ezimbi;
- i-hemorrhage;
- isilonda esisisu;
- izifo ze-vascular disorders.
Akukhuthazwa ukusebenzisa le mveliso ngexesha elifanayo kunye nama-antiplatelet agents. Olu nxu lungozi ebomini, kuba lukhuphula kakhulu umngcipheko wokulapha phantse kathathu. Ukuba kukho izibonakaliso zokusetyenziswa kwePrax kwaye ugqirha wagqiba ekubeni anikeze eli liyeza, ngoko kuyimfuneko ukucima ukutyiwa kweminye iindidi ze-anticoagulants. Akunconywa ukuba enze unyango olunjalo ngonyango kwizigulana ezingaphantsi kweminyaka eyi-18 ubudala, kuba akukho datha yekliniki kwimiphumo yokusetyenziswa kwalo nyaka.