Zollinger-Ellinson Syndrome

Igama elinzima kangaka liyi-tumor. Ngokuchanekileyo, imeko yezempilo phambi kwesikhumba. I-syndrome ye-Zollinger-Ellison ifunyaniswa ukuba ne-pancreatic tumor, kaninzi kangako - i-duodenum okanye isisu. Iimpawu zesi sifo zihlala zidideka kunye nesilonda esiswini esiswini, ngenxa yonyango olufunekayo lunikiweyo ngexesha. Ukwazi uhlobo lwesifo, unokuphepha iingxaki ezinxulumene nazo. Ngale nto uze uthethe kwinqaku.

Isifo seZollinger-Ellison

Ingxaki ebalulekileyo kukuba izigulane ezininzi zine-Zollinger-Ellison syndrome ebonakaliswe yimpawu ezifana nezilonda . Ngoko ke, zombini iimviwo kunye nokuhlalutya kwenziwa ngokuhambelana. Kubalulekile ukuba uqonde ukuba i-gastrinomas - izicubu ezivela kwi-Zollinger-Ellison syndrome - ezinokubakho zibangelwa kakubi. Kwaye kunjalo, uyazi, awukwazi ukuhlala. Nangona i-gastrinomas iphinda ikhulise ngobukhulu ngokukhawuleza, iyakwazi ukuqala i-metastases kumalungu angummelwane, ikhupha ingxaki efanayo.

Kuze kube yimini, kuyisiko ukuhlukanisa isifo ngale ndlela ilandelayo:

1. I-gastrinomas engabodwa, esoloko ihlala kwiipakreta.
2. Amathumbu amaninzi angasasazeka kwi-pancreas, nangona isisu esiswini.

I-Hypergastemia inokuphuhliswa phambi koogonyamelo kwi-thyroid gland, i-adrenal gland, kwaye ithathwa njengesona sizathu esibalulekileyo sokubonakala kwe-Zollinger-Ellison syndrome.

Iimpawu eziphambili zesifo

Ngokuqhelekileyo kwizigulane ezine-Zollinger-Ellison syndrome ngokubhekiselele kwimvelaphi yesifo esisisigxina, isifo sesilonda siphuhlisa. Ngoko ke, ngenxa yesininzi, iimpawu zezifo ziyafana. Ukubonakaliswa okubalulekileyo kwesi sifo kujonge oku:

1. Uphawu oluphambili kwi-Zollinger-Ellison syndrome lomelele, luhlala luhlungu kwaye luhlala luhlungu intlungu ephezulu kwesisu.
2. Ukugxeka kufuneka kubangele ukupheka kwentliziyo kunye ne-asidi yokuvutha emlonyeni, ebonakala emva kokuqhuma.
3. Isigulane siphume kakhulu.
4. Inqwalaselo kufuneka ihlawulwe kwakhona kumlinganiso wesihlalo. Ukuhlala uhudo, izigulane eziphambili ziyimpawu ezibalulekileyo zesifo.
5. Ngokuqhelekileyo, kwisifo se-Zollinger-Ellison, i-reflux esophagitis iyaqhubeka, nto leyo ibangele ukuba i-constriction ne deformation ye-esophagus.
6. Ukuba eso sifo sidlulile kwiimeko ezingabanjwanga, kukho ukunyuka kwesibindi.

Xa ufumene ubuncinane impawu ezilapha ngasentla ze-Zollinger-Ellison syndrome, kufuneka ukhawuleze ubone ugqirha. Kungenzeka ukuba izikhalazo azilungelelwanga, kodwa uphando olunzulu aluyi kuba nayiphi na imeko.

Unyango lwe-Zollinger-Ellison syndrome

Ukufumanisa izilonda ezavela ngenxa yesifo seZollinger-Ellison, kufuneka uhlalutye ngokubanzi. Oku kuya kunceda ukuphepha impazamo yezokwelapha kunye negalelo ekuqeshweni kwonyango olululo ngokwenene.

Ingundoqo yonyango lwe-Zollinger-Ellison syndrome ngokuyinhloko ukususa isisu. Kule meko, emva kokusebenza, kubaluleke kakhulu ukujonga imeko yeemeko ezichaphazelekayo kunye nezichaphazelekayo. Kubalulekile ukulungelelelwa ukuba ngexesha lokusebenza, i-metastases ezishiya kwi-tumor zifumaneka rhoqo, kungakho kungekho-30% yezigulane zonyango ngokupheleleyo.

Inkxaso yomzimba ngexesha loonyango (kunye ngamanye amaxesha kulo lonke ixesha lobomi bakhe) lunokusetyenziswa kweziyobisi ezikhethekileyo ezinciphisa inani le-hydrochloric acid.

Ngethamsanqa, izibikezelo ze-Zollinger-Ellison syndrome zibonakala zihle ngakumbi kunezinye izicubu ezibi. Ngaphandle kwimiba ye-metastases, izigulane zilawula ukubuyisela kwaye zinqobe umda we-five-year survival.