I-Clavulanic acid yinto ekhethekileyo echaphazelekayo kunye ne-penicillinase kwaye ayisebenzise. Ingabonakala ekubunjweni kwezidakamizwa ezininzi ezidibeneyo. Ukongeza, i-clavulanic acid ingasetyenziswa ngokufanayo ne-beta-lactam antibiotics.
Indlela yokwenza i-clavulanic acid
Iingcali zithi i-clavulanic acid i-metabolism. Le nkunkuma iyakwazi ukuvelisa i-antitimicrobial effect effect. Iziyobisi eziqukethe i-clavulanic acid ziboniswa ukuba zisetyenziswe kwizifo ezahlukahlukeneyo ezivuthayo ezibangelwa zizifo ezinobungozi kunye neebhaktheriya.
Isakhiwo seamoleksi ye-clavulanic acid ifana ne-antibiotics yechungechunge lwe-penicillin. Yingakho ukudibanisa kwabo kwiindawo zokujonga i-pharmacological kuthathwa ngokugqithiseleyo. Uhlobo oluphambili kukuba kwi-asidi endaweni ye-thiazolidine kukho iringe ye-oxazolidine. Kodwa ukuhambelana kwezinto akuphazamiseki.
Ukungena emzimbeni, i-clavulanic acid inqanda i-beta-lactamase - i-enzymes ebhaktheriya, ukubonakala kwayo ebangela umsebenzi obalulekileyo we-microorganms. Ngokuqhelekileyo, umgaqo wezenzo ze-clavulanic acid ilula: ngokusebenzisa igobolondo elikhuselayo, lingena kwiiseli zebhakteria kwaye "liguqula" i-enzymes ephakathi. Ngaloo ndlela, loo nto ayivumeli ii-virus kunye neebhaktheriya ukuba zande.
Njengoko umkhuba ubonisile, emva kokunciphisa, ukunciphisa i-beta-lactamase kuthathwa ngokungenakwenzeka. Ngenxa ye-microorganisms i-pathogenic ayinakukwazi kuphela ukukhula, kodwa iphinda ilahlekelwe ithuba lokuphucula ukuchasana ne-antibiotics ebenza baphephe.
Ukusebenza kwezinto eziphezulu kakhulu. Kwaye loo miqolo yeebhaktheriya kunye neentsholongwane eziye zakwazi ukukhusela i-Amoxicillin kunye ne-Ampicillin zitshabalaliswa yinto eyenziwa yi-clavulanic acid. Oko kukuthi, imbonakalo yezenzo zezidakamizwa ezidibeneyo zininzi kakhulu kunokuba zenziwe ngamayeza aqhelekileyo.
Ngokwenene, iziyobisi kunye ne-clavulinic acid zithathwa ngomlomo, kodwa ngezinye iimeko, ukuphathwa kwazo ngokubambisana kuthathwa njengongempumelelo. Ngaloo ndlela, akukho zichaso malunga nesilungiso, akufanelekanga kuphela kwizigulane ezingaxhaswanga. Kwiimeko ezinzima kakhulu, i-clavulic acid enxulumene ne-Amoxicillin kunye neTicarcillin inokuthathwa nakwabesetyhini abakhulelweyo.
I-Augmentin - i-Amoxicillin ene-clavulanic acid
Le ngenye yezona zinto ziyaziwa ngamayeza. Isilwayo siboniswa ngolu hlobo lwezifo:
- i-bronchitis (kubandakanywa kwifomu engapheliyo);
- pneumonia;
- ukungabikho kwemiphunga ;
- ulwasulelo lwebhaktheriya;
- i-cystitis;
- peritonitis;
- osteomyelitis;
- angina;
- septicemia;
- pyelonephritis.
Isisombululo se-Augmentin kwisigulane ngasinye sikhethwe ngabanye, kuxhomekeke kwifomu kunye nobunzima besifo, imeko epheleleyo yesigulane, ubudala bakhe, ukuxilongwa kwe-concomitant diagnostics. Unyango kunye nesilwanyana kufuneka uhlale ungaphantsi kwamahlanu, kodwa ungapheli iintsuku ezilishumi elinesine.
I-Flemoxin ene-clavulanic acid
Le yinye inhlanganisela eyaziwayo, ebizwa ngokuba yiFlemoklav. I-antibacterial agent ebiza i-Flemoxin yangaphambili, kodwa ixabiso layo lichanekile ngokufanelekileyo.
Isixhobo sisetyenziselwa ukuphatha iinkqubo ezahlukeneyo ezivuthayo:
- otitis media;
- pharyngitis ;
- bronchitis;
- ipneumonia;
- izifo zonyango;
- ukuvutha kwesidumbu;
- izilonda ezithintekayo nezivuzayo zamathambo namalungu.
UFlemoklav ukhululwa ngendlela yeepilisi ezityumkileyo, ngenxa yokuba ukuphumelela kwayo kuphakama ngakumbi.