I-Irunin ngummeli we-antitifungal. Lo lukulungiselelo olubanzi, oluvela kwi-triazole. Umgaqo we-Irunin (kunye nawo amaninzi afana nawo), usekelwe ekuthintela ukuhlanganiswa kwe-ergosterol kwiimbilini zee-cell. Isilwanyana sisebenza kakuhle, kodwa ngelanga, ngenxa yezizathu ezahlukahlukeneyo, kungekhona wonke umntu onokuyithatha.
Ziziphi izizathu zesiganeko se-Irunin?
Isilwanyana sisebenzisana neentlobo ezahlukeneyo zefungi: i-dermatophytes, imvubelo, iimbumba. I-Irunin ine-bioavailability ephezulu. Isiza ngokukhawuleza siqokelela emzimbeni, kwaye ngokufanelekileyo, kwaye inyathelo liqala ngokukhawuleza.
Nika i-Irunin ngendlela yeefomsules kunye neepilisi zamanzi kunye neengxaki ezifana nale:
- keratitis;
- dermatomycosis ;
- onychomycosis;
- pityriasis lichen ;
- hertoplasmosis;
- sporotrichosis;
- i-mycosis;
- blastomycosis;
- cryptococcosis;
- candidiasis;
- aspergillosis;
- Candidomycosis;
- paracoccidiomycosis;
- candidiasis.
Kodwa, njengawo nayiphi na mafutha okanye iipilisi, i-Irunin inqatshelwe kwisicelo:
- Amachiza akufanele aphathwe ngenxa yezi gulane ezinokuxhatshazelwa komntu kumacandelo okwakhiwa.
- Kuyinto engathandekiyo ukuthatha iipilisi kubafazi abakhulelweyo. I-Irunin ikhetha oomama bokamva kuphela kwiziganeko eziqhelekileyo, xa iinzuzo ezilindelekileyo ziya kulungelelanisa umngcipheko.
- Akukhuthazwa ukusela amacwecwe ngeTerfenadine, Lovastine, Pimozil, uSimvastin.
Yintoni engathatha indawo ye-Irunin?
Kuyafana nomgaqo wezenzo zamachiza amaninzi. Uluhlu lwezifana eziphambili ziquka:
- Orugnal;
- Itraconazole;
- Ikhefu;
- Itramikol;
- Orunite;
- Rumikoz;
- Tecnazol;
- Orungamine;
- Miconiol.
Ukuthenga iziyobisi, kufuneka uqikelele ukuba uninzi lwezifaniso ze-Irunin azincinci.