Izidakamizwa ezichithwa ngokunyanisekileyo ngamanye amaxesha ziqulethe ii-antibiotics ekuqulunqweni. I-ejensi ephantsi kwengqwalasela ayisebenzisi kubo, nangona i-analgesic esebenzayo. Nangona kunjalo, i-Nimesil kunye notywala abanakukwazi ukutshatyalaliswa ngolunye usuku, kuba oku kungakhokelela kwimiphumo engapheliyo emzimbeni.
Ukunxibelelana kweNimesil notywala
Ukuhlanjululwa kwe-ethyl yotywala kwenzeka kwiqindi, ngelixa kuvelisa into echazayo ebizwa ngokuthi i-acetaldehyde. Iingxenye ezinxilisayo zobunxila azinakuchukumisi ukufa kweseli, kanti ukusetyenziswa kakubi kotywala kunokukhokelela ekutshintsheni izicubu ze-hepatic ngamathambo axhumeneyo. Ngako oko, iziphuzo ezinxilisayo zinomphumo onobungozi emzimbeni, zonakalisa iiseli zesibindi. Icandelo elisebenzayo leNimesil yi-nimesulide, into engeyiyo-steroidal evuthayo-ukuvuvukala, eyongezwayo kwi-anesthetizing, ivelisa i-antipyretic. I-toxin ebuthakathaka, efana ne-acetaldehyde, inokwazi ukutshabalalisa iiseli zesibindi kumaxabiso angaphezu kwezocetywayo kwimigaqo. Eminye imiphumo emibi kwipilisi enombuzo, kuboniswa ukuba enye yemiphumo emibi yeyeza unyango ingaba kuphulwa komsebenzi wesibindi, kunye ne- hepatitis . Ngako oko, uNimesil kunye notywala abanakunqweneleka ukudibanisa, kuba ukusetyenziswa ngokufanayo kwezinto ezinobungozi kwi-body-forming body-reinforces action.
Ngaba kunokwenzeka ukuthatha uNimesil ngotywala, kwaye yintoni ukusebenzisana kwabo?
Kulo myalelo kwisiza esicacisiwe, akukho nto ibonisa ukuba uNimesil notywala abahambelaniyo, kwaye akukho ncazelo yeendlela zokusebenzisana. Kodwa ku funeka kuqatshelwe ukuba imetabolism (ukucoca) ye-nimesulide iyenzeka ngokuthatha inxaxheba kwi-enzyme ekhethekileyo-isoenzyme cytochrome. Njengoko kwavela, ikhuthaza ukuphuka kwe-ethanol i-compounds kwisibindi. Ngako oko, ukusetyenziswa kwangaphandle kwesilwanyana ngotywala kutyhubela ukuveliswa kwe-enzyme ngokugqithiseleyo kwaye, ngenxa yoko, ukwanda komthwalo onobuthi kwisibindi.
Ngaphezu koko, ngenxa yokungabikho kophando malunga nokusebenzisana kukaNimesil neziphuzo ezinxilisayo, abukho ubungqina bokuthi esi sixhobo siyakunceda njani. Phakathi kweengcali, kukholelwa ukuba utywala luvimbela umsebenzi weziyobisi, kwaye isenzo esaneleyo se-analgesic asifezekanga.
Enye yemiphumo eyingozi kakhulu yokuthatha uNimesil ngotywala yithuba lokungafumani imiphumo echaphazelekayo yonyango njengophala kwangaphakathi kwindlela yokuxhamla esiswini ngenxa yobunxila. Kwilizwe elingenalwazi, ukungawunaki uphawu olunjalo kunokukhokelela ekufeni.
I-Nimesil emva kokunxiliswa kotywala
Kukho iimeko xa emva komthendeleko unesihloko esisinyanisekileyo okanye sisifo esiyingozi esingapheliyo, sihamba kunye neengcamango ezingathandekiyo. Ngokwemvelo, kufuneka ukhawuleze