I-Dibasol yilezi ziyobisi ezenziwe ngamaqela e-antiotropasmodics. Esi sichazi ngenye yezinto eziphumelelayo zenzululwazi zeSoviet kwintsimi ye-pharmacology njengesixhobo esisebenzayo nesingenakulimala. I-Dibasol iveliswa ngendlela yamacwecwe kunye nesisombululo se-injections kwi-ampoules. Into esebenzayo yeziyobisi yi-bendazole.
I-Pharmacological action of dibasol
I-Dibazol inefuthe kwimibhobho ye-muscle, imisipha evulekileyo yemithwalo yegazi kunye neempahla zangaphakathi. Ukuphelisa i-spasms, ukunciphisa ithoni yemithambo yegazi kunye nokukhuthaza ukwandiswa kwazo, ngokunjalo ukunciphisa izinga lexinzelelo legazi kwaye kusebenze ukunikezelwa kwegazi kwiindawo ze-myocardial ischemia. Nangona kunjalo, i-hypotensive effect yeli gciwane lifutshane.
Ngokuchaphazela ukusetyenziswa komtya womthambo, le nkunkuma iququzelela ukuhanjiswa kwe-synaptic transmission (neurotransmission). Kwakhona, i-Dibazol inomsebenzi ochanekileyo, osebenza ngokukhawuleza, owanceda ukwandisa ukungabikho kwamandla omzimba kwimiphumo eyahlukeneyo.
Imiqondiso yokusetyenziswa kweDiabazole:
- Uxinzelelo lwegazi oluphezulu kwiinqanaba zokuqala;
- ntlekele ;
- i-coronary spasm;
- izifo zengaphakathi zangaphakathi ezibonakaliswe ngentsholongwane yezihlunu ezigqithisiweyo (isilonda se-peptic, i-renal, intestinal ne-hepatic colic, i-spasms yomgcini-masango kunye namathumbu, njl.);
- izifo zesimiso se-nervous (poliomyelitis, polyneuritis, ukukhubazeka kwesibindi somzimba, njl);
- izifo zentsholongwane kunye nezifo zentsholongwane.
IDibasol njenge-immunomodulator
Ukusetyenziswa kwe-dibazol ukuphucula ukukhuselwa kwabaxhaswa ngugqirha owaziwayo kunye ne-pharmacologist, uProfesa Lazarev. Ngokwezifundo eziqhutywe, ukuthatha amanyathelo amancinci ale mayeza ngenjongo yokuthintela izifo zentsholongwane ngexesha leengculazi zenze ukuba kunokwenzeka ukunciphisa iziganeko malunga nama-80%.
I-Dibazol ikhuthaza ukuveliswa kwe-interferon ngomzimba, ukwanda kwinqanaba le-endorphins, i-interleukins kunye ne-phagocytes ezihambelana nezixhobo ezikhuselekileyo zokukhusela umzimba. Ukongezelela, kwafunyaniswa ukuba ukusetyenziswa kwe-interferon yayo kubonwa nakumaxesha xa intsholongwane sele isulelekile kwiintsholongwane ze-influenza okanye izifo zokuphefumula. Iinkcukacha ezivela kwizilingo zeklinikhi zibonisa ukuba xa uqala ukuthatha i-Dibazol ngosuku lokuqala losulelo oluphefumulayo lokusuleleka kwintsholongwane okanye umkhuhlane, oko kuza kubuyiselwa ngokukhawuleza kwaye iimpawu ziya kuthi zingabi ncinane.
Isilwanyana sichaphazela kakuhle emva kokugonya, sishukumise umveliso we-immunoglobulins, ngaloo ndlela ukwandisa umkhuhlane owenziwe emva kokungeniswa kwesitofu. Impembelelo ye-dibazol iyasetyenziswa ngokuchaphazela inkqubo ye-nervous central, ukukhuthaza iindlela eziphambili ze-homeostasis ukugcina ukuhlala kwimeko yangaphakathi yendalo kunye nemisebenzi yayo eyintloko.
Isifo seDibazol
Ukukhusela i-catarrhal kunye neentsholongwane zentsholongwane, kunye nokuphucula ukukhuselwa komzimba, i-Dibazol inconywa
Electrophoresis nge dibasol
Ulwaphulo lwe-Dibazol lungenziwa ngeenkqubo ze-electrophoresis. Kule meko, isisombululo seziyobisi sisetyenziselwa i-electrode pads kwaye phantsi kwezenzo zombane wombane ungena emzimbeni ngesikhumba, ukubonelela ngempumelelo i-vasodilating ne-spasmolytic effect. Ngokubanzi, i-electrophoresis ne-dibasol isinconywa ngezifo ze-neurological.