Ijoni lisila i-Pilocarpine

I-Pilocarpine ijongana liso kwisiseko se-alkaloid, esetyenziswa ngokubanzi ukunciphisa uxinzelelo lwe-intraocular kunye nokunyangwa kwe-glaucoma.

Inkqubo yesenzo sePilocarpine ngenxa yokuba ibangela ukunciphisa umsila we-ciliary and circular muscle we-iris ngenxa yesiphumo esishukumisayo kwi-M-cholinergic receptors. Esi siphumo sihambelana nokuphucula ukuphuma kwe-intraocular fluid kunye nokunciphisa umfundi. Ngenxa yoko, iinkqubo zokuxilisa kwiisisculi zamehlo ziphucula, kwaye ukunyanzeliswa kwe-intraocular kunciphisa.

Ukubunjwa kunye nefomu yokukhululwa

Isilwanyana sifumaneka njengesisombululo se-1%, kwiibhotile zeplastiki ezine-dropper, ivolumu 10 okanye 5 ml.

Ukubunjwa kwamaconsi iliso kubandakanya:

• i-pilocarpine hydrochloride (10 mg nganye nge-1 ml yesisombululo, isistim esebenzayo);
• i-boric acid;
• ngamanzi ukwenzela inkunkuma.

Iziganeko zePilocarpine ziziyobisi:

• Salazon;
• Oftan Pilocarpine;
• I-Pilocarpine-Dia;
• Ixesha lePilocarpine;
• Pilocarpine-Ferein.

I-Pilocarpine - imiqondiso yokusetyenziswa

Amaconsi e-Pilocarpine asetyenziswa ekunyangeni:

• Ukuhlaselwa ngokukrakra kwe-glaucoma yokuvalwa kwe-angle;
• glaucoma evulekile kwaye engapheliyo;
• ne glaucoma engavaliyo (phambi kokuhlinzwa);
• i-glaucoma yesibini, eyaphuhliswa ngenxa yokuqhwala kwi-vitreous;
• i-retinal thrombosis;
• i-atrophy ye-optic nerve ;
• ukuguqulwa kwamabala e-retina.

Kwakhona, isilwanyana sisetyenziselwa ukunciphisa abafundi ngokugqithiseleyo kwezinto eziqhelekileyo, ngenjongo yokuxilonga kunye nokungenelela kwamanyathelo athile.

Imiyalelo yokusetyenziswa kweelahla zePilocarpine

Ubuninzi besicelo kunye neli dose leziyobisi ngokuqhelekileyo ligqitywe ngugqirha.

Ngokuqhelekileyo, kunye ne-glaucoma eyintloko, le nkunkuma ifakwe kwi-1-2 yehla kathathu ngosuku. Xa unyango lwe-glaucoma yokuvala i-angle-closure, i-frequation of instillation iyahluka rhoqo emva kwemizuzu engama-15 kwiyure yokuqala, ukuya kuma-3-6 maxesha ngosuku emva kokuhlaselwa.

Ngokuqhelekileyo, amaconsi asePilocarpine aqaliswa imizuzu engama-30-40 emva kokufaka isicelo, kwaye umphumo ophezulu uphumelelwa emva kweeyure eziyi-1.5-2. Isilwanyana singene ngokungena kwi-cornea kwaye ayifumani ngokukodwa kwintsipheko.

Ukungqinelana kokusetyenziswa kwezi gxobhozo kubandakanya ukuxhomekeka komntu ngamnye kumacandelo, izifo zamehlo kunye neemeko zokuhamba emva kokunciphisa umfundi.

• keratitis;
• irit;
• iridocyclitis .

Ukulumka kufuna ukusetyenziswa kwe-pilocarpine kwizigulane ezineqondo eliphezulu le-myopia kunye ne-retinal detachment. Xa ukhulelwe, qalisa ukuba le mpendulo ayikhuthazwa.