I-Amitriptyline isilwanyana esixinzelelekayo esivela kwiqela lama-tricyclic compounds. It has calming, analgesic, antihistamine, hypnotic, antiulcer effect. Ngokuqhelekileyo esi sigqeba sinqunywe ukudakumba kwezidalwa ze-genesis, i-neuroses, i-psychoses kunye nezinye izifo.
Amacwecwe e-Amitriptyline anamandla okwaneleyo ukuvelisa iziphumo zomzimba kumzimba. Ukongezelela kwimpembelelo echaphazelekayo yonyango yale nkunkuma, eyenziwa ngokukhawuleza, izigulane ezininzi zibona ukubonakala kweziphumo ezahlukahlukeneyo xa zisetyenzisiweyo. Kwiimeko ezininzi, iziphumo zempembelelo zivela kuphela emva kweentsuku ezi-1 ukuya kwezi-2 emva kokuqala kweyeza zonyango. Khawucinge ngemiphumo emibi ye-Amitriptyline, kutheni kwenzeka, kwaye ngubani unyango olukhutshelweyo.
Imiphumo emibi ye-Amitriptyline
Ngokuqhelekileyo, ukubonakala kwemiphumo emibi ye-Amitriptyline inxulumene nokugqithisa kwayo (idosi ephezulu yesicatshulwa ngumntu ngamnye). Kwakhona, zinokuthi zihambelane nelokuba ukuba xa usebenzisa isicelo sonyango umntu uguqula ngokucacileyo indawo yokulala ekuhlaleni nasekumiyo (zonke iintshukumo mazibe zihamba kakuhle). Isenzo esichasayo sibonakaliswe ngokusebenzisana kwe-Amitriptyline namanye amayeza. Phakathi kwazo:
- i-monoamine oxidase inhibitors;
- antipsychotics;
- anticoagulants;
- glucocorticoids, njl
Phakathi kweempembelelo ze-Amitriptyline siyaqaphela oku kulandelayo:
1. Ukususela kwicala lokutya:
- intlungu yesisu;
- ukuguquka ;
- isicefe
- ukuhlanza;
- i-jaundice ngenxa yeengxaki ze-congestive kwi-biliary tract;
- iziphazamiso zesitopu;
- utshintsho kwindlela yokuqonda;
- umsebenzi wesibindi.
2. Ukususela kwicala le-cardiovascular system kunye ne-hematopoiesis system:
- ukuhluleka kwentliziyo;
- ukunciphisa uxinzelelo lwegazi;
- ukungcola;
- ukuphazamiseka kwenkqubo yokuqhuba intliziyo;
- utshintsho kwipesenti ze-erythrocytes, i-leukocytes kunye neeplatelet;
- utshintsho kwi-electrocardiogram.
3. Ukususela kwicala lenkqubo:
- iingcamango;
- u buqhetseba;
- kutyhafa;
- ukulala okanye ukulala;
- ukuvela kokuhamba okungalawulwayo kwezandla kunye neenyawo;
- ukudideka kwengqondo;
- ukuthuthumela kwentloko kunye neengalo;
- intloko;
- zixhala;
- ukukhwela;
- ukuxhwaba;
- ukunciphisa nokwandisa ukunyuka kwamanzi.
4. Kwinqanaba le-endocrine:
- utshintsho kwisifiso sesondo;
- utshintshile kumxholo weglucose;
- kuncipha kwi-ion ioni;
- Ukwandiswa kweengcambu zamathambo.
5. Ezinye iziphumo ezichaphazelekayo, kuquka ezo zidibaniswa nomphumo wokwelapha weziyobisi:
- iintlobo ezahlukeneyo zokubonakaliswa (i-angioedema, i-hives, itching, etc.);
- uxinzelelo lwe-intraocular;
- ukungabonakali;
- umlomo owomileyo;
- ingxolo ezindlebeni ;
- ukulahlekelwa kweenwele;
- umkhuhlane;
- ukucoca rhoqo, njl
Amitriptyline kunye notywala
Akunjalo na ukusetyenziswa kotywala kotywala kunokusetyenziswa xa kuphathwa le nkunkuma. Ukusebenzisana kwe-amitriptyline kunye notywala kunemiphumo ecindezelayo kwinkqubo yesistim ephakathi, kwaye kunye nokudakumba kweziko lokuphefumula, kunokubangela ukuxhatshazwa nokufa.
Ukungqinelana kokuthatha i-Amitriptyline:
- ukukhulelwa kunye nokuhlaselwa;
- Ukungaphumeleli kwentliziyo kwinqanaba lokunciphisa;
- i-infyoction ye-myocardial (isigaba esibukhali kunye nokubuyisela);
- uxinzelelo lwegazi oluphezulu;
- ukuphulwa komsebenzi we-myocardial;
- isigaba esiqatha sezilonda zesilonda;
- isibindi nesifo seengtso ngexesha elibi;
- buthathaka ithoni yeendonga ze-bladder;
- isithintelo samathumbu.