Xa i-metabolism emzimbeni, i-hemoglobin ifakwe kwisibindi, yenza i-bilirubin njengento yokubola. Itholakala kwi-serum kunye ne-bile. I-Bilirubin idityaniswe emzimbeni kunye nomchamo kunye namanzi, kunye ne-bile. Ukuba izinga le-bilirubin landa, libonakalisa ngohlobo lwe-yellowing- yellowundice .
Xa uhlalutya umxholo we-bilirubin kwi-plasma yegazi, qwalasela iindidi ezichanekileyo kunye ezingekho ngqo kule pigment. Iintlobo ezimbini ziqhelekileyo ze-bilirubin. Ngokuthe ngqo-oku kukuthi i-pigment isele iboshwe kwiiseli zesibindi kwaye ilungele ukususwa, kwaye ingqalileyo yenziwe ngoku kutshatyalaliswa kwaye ayizange ifakwe. Umxholo we-bilirubin egazini ubonisa indlela ukusebenza ngayo isibindi kunye ne-bile ducts. Ukwandisa izinga le-pigment ukuya kumanqaku aphezulu yinto eyingozi kwaye ifuna inyathelo elikhawulezayo.
Indlela yokwenza uhlalutyo lwe-bilirubin?
Kukho imithetho emininzi yokuthatha uvavanyo lwegazi kwi-bilirubin eqhelekileyo:
- Ukuze kuqinisekiswe umgangatho we-bilirubin, isampuli yegazi isenziwa kwi-vein ngaphakathi kwe-elbow yengalo. Iintsana zithatha igazi kwisithende okanye emthanjeni entloko.
- Ngaphambi kokuba uthathe uvavanyo ubuncinane iintsuku ezi-3 awukwazi ukuthatha ukutya okunamafutha kwaye kufuneka ubalekele utywala.
- Uhlalutyo lwenziwe kuphela kwisisu esingenalutho. Kufuneka ulambile ubuncinane ubuncinane kwiiyure eziyi-8. Njengomthetho, igazi lithathwa ekuseni. Kubantwana akukho mingcele.
Isiphumo sohlalutyo singathonyelwa yizinto ezilandelayo:
- ukuthatha ikhofi kunye neziyobisi ze-caffeine;
- ukuthatha iMarfarin, Aspirin, Heparin;
- ukutya kunye nendlala;
- ukuthatha amalungiselelo e-cholagogue okanye i-decoctions yamacube, amayeza esibindi;
- khulelwa.
Imigangatho ye-bilirubin ekuhlolweni kwegazi
Isiqhelo se-bilirubin eseleyo kubantu abadala sisuka ku-3.4, (ngokweminye imithombo evela ku-5.1) ukuya kwi-17 micromolar ngeyure.
Ingqungquthela engqalileyo ingama-70-75%, ukufundwa kwi-micromoles nganye kwimizuzu ukusuka ku-3.4 ukuya kwi-12. Iqhekeza elichanekileyo lihluka ukusuka kwi-1.7 ukuya ku-5.1 micromolar ngeyure. Eminye imithombo ithi inqununu ingaqwalaselwa ukusuka kwi-0 ukuya kwi-3.5 micromolar ngeyure.
Kufuneka kuqatshelwe ukuba kubafazi abakhulelweyo inqanaba elincinci le-bilirubin ngokuqhelekileyo kuthathwa njengesiqhelo. Kwiintsana, i
Bilirubin ekuhlalutheni umchamo
Ukuba i-bilirubin ifumaneka ekuhlalutheni umchamo, lo ngumqondiso wokuqala wokungasebenzi kwimbindi kunye ne-bile. Uhlalutyo lubonelela ngokukhawuleza kwezifo ezifana:
- i-cirrhosis ;
- i hepatitis;
- izifo ze gallbladder;
- nomhlaza.