Bisoprolol analogues

I-Bisoprolol isilwanyana esisoloko sichazwe kwizigulane ezinezifo zengqondo kunye negazi.

Izimpawu zokusetyenziswa kwazo zilandelayo:

• isicic heart disease ( angina );
• ngxinzelelo lwegazi;
• tusycardia;
• ukuhluleka kwentliziyo engapheliyo;
• ukuphazamiseka kwentliziyo;
• i-arrhythmia ne thyrotoxicosis kunye ne-mitral valve prolapse.

Njengamanye amayeza, i-bisoprolol inezifana zayo. Impembelelo yazo eyona nto ibalulekileyo, bonke banciphisa uxinzelelo lwegazi. Kodwa kukho ukungafani phakathi kwabo.

Yintoni engayenza indawo ye-bisoprolol?

Iziganeko zezilwanyana zeBisoprolol zilandelayo:

• Metoprolol;
• Carvedilol;
• Egilok;
• Betaxolol;
• Nebivolol;
• Propranolol.

Ukuqhubela phambili siya kuqwalasela, kwintoni na umehluko phakathi kwamachiza-afana neBisoprolol.

Yintoni engcono - i-metoprolol okanye i-bisoprolol?

I-Metoprolol isifananiselo esincinci ye-bisoprolol. Ngoko, izibonakaliso zokusetyenziswa kwazo zifana ngokufanayo. Ngaba ngaba kukho umehluko phakathi kwezi ziyobisi? Kuvela apho kukho. Ukuthelekisa iimpahla zabo ze-pharmacological, umntu unokufikelela kwisigqibo sokuba i-bisoprolol ineenzuzo ezininzi, esiza kuxoxa ngazo.

Isiqingatha-bomi seBisoprolol ngama-10-12 iiyure, kwaye kwiMetoprolol ngamahora ama-3-4. Ngenxa yoko, i-bisoprolol inokuthathwa kanye ngosuku, i-frequency ye-metoprolol intake iphezulu kakhulu.

Ukubopha i-metoprolol kwiiprotheni ze-plasma ngu-88%, ngelixa i-Bisoprolol le ngcaciso ifikelela kuma-30% kuphela. Kwaye kunokuba isalathisi sincinci, ukulungiselela kuyasebenza. Ngoko ke, i-bisoprolol iyasebenza.

I-Bisoprolol i-beta-blocker ye-amphophilic, inqabile kumanzi kunye namafutha. Ngako oko, i-Bisoprolol ingena emngceleni we-brain-brain and is reducted by the kidneys and liver. Ngoxa i-metoprolol isetyenziswe kuphela ngesibindi, ngokufanelekileyo, umthwalo kweli candelo uya kuba mkhulu.

Carvedilol okanye i-bisoprolol - engcono?

I-Carvedilol yenye into efana neBisoprolol. Njenga-metoprolol, i-carvedilol i-metabolized kuphela kwisibindi. Ngoko ke, kwizigulane ezineesibindi sesibindi, ixesha lokutya kweziyobisi kunye neelayi kufuneka linciphise. Ngokungafani neBisoprolol, iCarvedilol kunye neMetoprolol ifinyelela kwi-barrier brain-barrier, okubangelwa yimiphumo emibini evela kwinkqubo yesantya.

Bisoprolol okanye i-Egiloc - engcono?

Phantse i-5% yesigqirha i- Egilok ikhutshwe emzimbeni ngomchamo. Bonke abanye baphunyezwa ngesibindi. Ngoko ke, ukulungiswa kwemilinganiselo kuyafuneka kwakhona ukuba kukho iingxaki kweli candelo. Kweminye imilinganiselo, isenzo seziyobisi siyafana, kwaye enye inokusindiswa ngokuphepha.

Ngaloo ndlela, kunokugqitywa ukuba izenzo zezilwanyana ezihlolwayo ziyafana. Zonke ziphantsi kwengcinezelo yegazi kunye nentliziyo. Kodwa ziqhutyelwe izifundo Izigulane zabhalwa kwinqanaba lexinzelelo lwegazi emini. Ngoko, ngenxa yoko, kwafunyaniswa ukuba izidakamizwa iBisoprolol zagcina ingozi yokuxilonga kwimizuzu yokusa yosuku olulandelayo. Ezinye izalathisi azikwazanga ukuziqhayisa ngale nto. Baye banqanda okanye banciphisa intshukumo yabo yokunciphisa igazi iintsuku ezingama-3-4 ngaphambi kokuba umthamo olandelayo weyeza kufuneka uthathwe.

Kwakhona, uphando lubonise ukuba i-Bisoprolol ilawula ngokufanelekileyo uxinzelelo lwegazi kunye nenqanaba lentliziyo emzimbeni ozolileyo kwaye phantsi kokusebenza ngokomzimba. Iziphumo zophando zibonakaliswa, ukuba kule Bisoprolol iphumelela ngakumbi, kuneMetoprolol.