Ngamanye iinkqubo zobomi bomsebenzi obalulekileyo womzimba womntu unikezwa ngamahomoni ahlukahlukeneyo, aveliswa yi-glands yangaphandle.
Yintoni i-ACTH?
I-adrenocorticotropic hormone yi-hormone ye peptide, eyenziwa yi-pituitary gland kwaye ilawula umsebenzi we-correnx ye-adrenal. Ngaloo ndlela, izilonda ze-adrenal zivelisa i-hormone ye-glucocorticoid kwaye zidibanise kwi-system circulatory system. Ukuba ihomoni ye-adrenocorticotropic iveliswa ngobuninzi, ukuhamba kwegazi kwanda kwi-adrenal gland, kwaye i-gland iyakhula. Ngakolunye uhlangothi, ukuba i-ACTH ingavelwanga ngokwaneleyo, inokwenza i-atrophy. I-horticone yeCorticotropic iyaziwa nangokuthi i-corticotropin, kwaye kwindlela yokwelapha isebenzisa igama elichanekileyo-ACTH.
Imisebenzi ye-horrenone ye-adrenocorticotropic (ACTH)
Inani lamahomoni elifihliweyo li-correnx corticon corticotropin lilawulwa ngumgaqo-mpendulo: inani le-corticotropin eveliswa ngumgudu we-pituitary ukwanda okanye ukunciphisa njengoko kuyimfuneko.
I-adrenocorticotropic hormone ithintela ukuveliswa kwezi hormone ezilandelayo:
- i-glucocorticoids, ngokuyinhloko i-cortisol kunye ne-cortisone, echazwe njenge-hormone ezichasayo kunye noxinzelelo.
- i-hormone yesini, ejongene nokuphelelwa ngumntwana kunye nomsebenzi wokuzala;
- ngokukodwa ukuveliswa kwe-adrenaline.
Ngoku kusekwe ngasentla, sinokugqiba ukuba i-horreno ye-adrenocorticotropic ixanduva ngqo:
- ukumelana nomzimba kwiintsholongwane;
- ukulungelelanisa kwiimeko ezintsha;
- ukusinda kwiimeko ezixinzelelekileyo;
- ukukwazi ukuvelisa inzala.
Umgangatho we-ACTH kwiinguqu zegazi kulo lonke usuku. Isixa esiphezulu se-corticotropin siyaphawulwa ngo-7: 8 ntambama ekuseni, kwaye ngokuhlwa, imveliso yayo iyancipha, iwele kumyinge wemihla ngemihla. Ukugqithisa ngokweqile ngokomzimba, uxinzelelo kunye neengxaki ze-hormone kubasetyhini zinokuchaphazela nomlinganiselo we-horrenone ye-adrenocorticotropic egazini. Amanqanaba okwandisa okanye ayancipha ama-ACTH anempembelelo embi ekusebenzeni komzimba kwaye ingaba sisifo sesifo esibi.
Ukuba i-ACTH iphakanyisiwe
I-adrenocorticotropic hormone iphakanyisiwe kwezi zifo:
- isifo sohlobo lwe-ectopic ye-ACTH xa le hormone iqalisa ukuvelisa isisu esiye savela kwelinye ilungu;
- Isifo sika-Addison okanye isifo sokuzalwa esiswini se-adrenal gland;
- Isifo se-Itzenko-Cushing, esenzeka ngenxa ye-pituitary adenoma;
- emva kokungenelela kokungeniswa kokususwa kweengqungquthela ze-adrenal;
- i-paraneoplastic syndrome, apho kukho ukuphendulwa ngokukhethekileyo kwegulane le-pituitary kwi-tumor ebulalayo, kaninzi kwi-pancreas.
Kwakhona, izinga le-ACTH landa ngokusetyenziswa kwamachiza athile, umzekelo, insulin, amphetamine okanye amalungiselelo e-lithium.
Ukuba i-ACTH iyancitshiswa
I-adrenocorticotropic hormone iyancipha kule mizimba elandelayo:
- Umsebenzi wehlisi wehla;
- kuncipha umsebenzi we-correnx ye-adrenal;
- xa kukho iiplastiki ze-adrenal glands;
- kunye neyeza le-hormonal, xa izigulane zithatha i-glucocorticoids;
- izifo zesifo se-bronchial and lung.
Kufuneka kwakhona kuqatshelwe ukuba ugqirha unokumisela uhlalutyo lwamanqanaba e-serum ye-ACTH ukuba ezi zilandelayo zibonakaliswe:
- ukhathala okwandisiweyo;
- ku xhatshazwa;
- isifo esingapheliyo;
- xi nzelelo.
Kwakhona, uphando olufanayo luqhutyelwa ukubeka iliso kwimeko yomzimba xa unyanga amayeza e-hormone.
Musa ukunyamekela ukutyunjwa kukagqirha ukuqhuba uhlalutyo lwezinga le-ACTH. Ngeziphumo zalo, unokubeka uvavanyo olufanelekileyo ngexesha kwaye uqale unyango olwaneleyo.