I-hormone ye-antidiuretic okanye i-hormone vasopressin yi-peptide. Iqulethe i-amino acid esele. Ubomi bemizuzu engama-2-4. Le hormone ikhiqizwa kwiindawo ezinkulu zee-hypothalamus, kwaye ukusuka apho ihanjiswa kwi-neurohypophysis. Ukuhamba kuqhutyelwa kwii-axon ngenxa yeeprotheni-vectors ezithile.
Imisebenzi ye-hormone vasopressin
Umsebenzi oyintloko wehommone kukulawulwa kwamanzi emetabolism. Ngoko ke, kuthiwa yi-antidiuretic. Emva kokuba inani le-ADH landa emzimbeni, umthamo we-urine ukhishwe ngokukhawuleza.
Kodwa ngokwenene kuvela ukuba i-vasopressin yi-hormone ehlukeneyo kunye nemisebenzi emzimbeni wenza imali ephawulekayo. Phakathi kwezinye ezibalulekileyo kuzo:
- ukwandisa umthamo wegazi ojikelezayo ngeempahla;
- yandisa ithoni ehamba kakuhle;
- ukwanda komsebenzi weeseli zegazi zeeplatelets;
- ukulungiswa kweempawu zeememori;
- ukunciphisa inani le-sodium egazini;
- oxidization of acid acids.
Imigangatho ye-vasopressin
Ukuba inani le-vasopressin lingqinelana nesiqhelo kwiziphumo zovavanyo, akukho zizathu zokukhathazeka. Iimpawu eziqhelekileyo zokubheka zibukeka ngathi:
- nge-osmolality ye-plasma 270-280 i-mosm / kg -
- 280-285 i-mosm / kg -
- 285-290 i-mosm / kg - 1-5 pg / mol;
- 290-295 i-mosm / kg - 2-7 pg / mol;
- 295-300 mosm / kg - 4-12 pg / mol.
Ngokomgaqo wesenzo, i-hormones vasopressin kunye ne- oxytocin inokujongwa njengento efanayo. Uhlobo oluphambili kukuba le mva iqulethe i-amino acid esele ngaphantsi. Kodwa oku akuthinteli i-hormone ekuboniseni umsebenzi othethekileyo ngokumalunga nokuvuselela ubisi, ngokomzekelo.
Ukunyanzeliswa kwe-hormone vasopressin
Ukuba inkunkuma emzimbeni ayanele, i-insipidus isifo sikashukela sinokukhula. Esi sifo sibonakaliswe ukucinezelwa komsebenzi wamanzi okuphinda uphuhliswe ngamathambo. Ukunciphisa izinga le-ADH lenziwa lula ngokusetyenziswa kwe-ethanol kunye ne-glucocorticoids.
Ukunyanzeliswa kwe-hormone antidiuretic vasopressin
I-ADH inokuveliswa ngamandla ngoku:
- ukukhululeka ngokomzimba nangokwenyama;
- ukuhluleka komntu;
- ukungabi namandla ;
- ukwehla kwindleko yegazi ejikelezayo kunye nombhede we-vascular;
- i-porphyria ephakathi;
- izicubu zeengqondo;
- pneumonia;
- i-meningitis enobuhlungu.
Ingxaki iyancipha kwi-plasma yegazi kunye nokukhululwa komchamo wexinzelelo eliphezulu.