I-PUVA-unyango luyindlela ekhethekileyo yokuphatha izifo zesikhumba ezahlukeneyo. Isitshixo salo sisefuthe elidibeneyo kwesikhumba samachiza anesityalo esivela kwisityalo (psoralenov (P) kunye nemisindo elula emilenze ye-ultraviolet.
Iinkcazo zePUVA unyango
Ininzi i-PUVA yokwelapha isetyenziselwa i-psoriasis yeenyawo kunye neentende. Le ndlela yokonyango imelana ngokufanelekileyo nale ntshoyo, nokuba ngaba izigulane ziye zahluleka ukuqhuba i-BUF-therapy. Unyango lwe- psoriasis kunye no-PUVA-unyango lunokuthi luqhutyelwe kwiimeko xa umntu enesifom okanye eqhubekayo yeplates ifom. Ngexesha leenkqubo, ukuphindaphinda kweeseli ezenza iqela lokugqithisa livalwe ngokupheleleyo, kwaye ekugqibeleni ukuphuhliswa kweeplates kumisiwe, kwaye ekugqibeleni kuyabalala.
Iimpawu zolu hlobo lonyango zibuye zise-dermatitis kunye ne-mushroom mycosis. I-PUVA-unyango lukwacetyiswa ukuba i-vitiligo. Kuya kuba luncedo nakwizo zi gulane eziye zachaphazeleka ngaphezu kwe-20-30% yesikhumba.
Ulwaphulo lwe-PUVA alukwenziwa ekhaya. Zonke iinkqubo zenziwa kuphela kwisigulana (ngokweziko eliqhelekileyo le-polyclinic okanye ezizodwa zonyango lwezifo zesikhumba). Izidakamizwa ezithathwe ngomlomo, okanye zisetyenziswe ngokusemgangathweni, kwaye emva kweeyure ezingama-2-3 ezichaphazelekayo kwiindawo zokugula zibonakaliswe kwimisebe ye-ultraviolet. Ixesha le-irradiation liqala imizuzu embalwa, kodwa landa ngeli seshoni nganye. Uninzi lwe-PUVA unyango lubandakanya iiseshoni ezili-10-30.
Ukuchasana nokunyangwa kwe-PUVA
I-PUVA-unyango unomsebenzi ophezulu (85%), kwaye iimpawu zokuqala zokuguqulwa kweembonakalo zesikhumba zibonakala emva kweenkqubo ezi-4-6. Le ndlela yonyango ixhomekeke kakuhle kwizigulane kwaye ayiyiloliso. Nangona kunjalo, akuyena wonke umntu onokuyisebenzisa.
Ukuchasana kwi-PUVA unyango:
- hypersensitivity kwi psoralen;
- i melanoma ebulalayo;
- lupus erythematosus ;
- aphakia;
xeroderma ye pigment; - i-albinism;
- porphyria;
- khulelwa.
Qaphela ukusebenzisa le ndlela yokuphatha izigulane ezinesikhumba esikhanyayo, i-cataract, uremrem kunye nokuhluleka kwezintso. Kwakhona, ungasebenzisi i-PUVA unyango kulabo abanesifo sokukhuseleka, okanye umntu oye waba nezicubu ezinzima. Izifo ezithintekayo ze-myocardial kunye nezinye izifo ezingavumelekanga ixesha elide ukuma, zivame ukukhusela ukuhamba kwekhosi epheleleyo.