Kwizinga eliphezulu, i-papaverine inciphisa ukukhushulwa kwentliziyo yesisipha, ithintela ukuqhutyelwa komzimba, kwaye inomphumo onobubele obushushu. I-Papaverine hydrochloride ifumaneka kwiifomethe, izisombululo zamagxina kunye ne-suppositories.
Iimpawu zokusetyenziswa kwe-suppositories kunye nepapaverine
I-Papaverine isetyenziselwa ukunciphisa i-spasms ye-muscle elula kunye ne- anesthetic xa kwenzeka iintlungu zibangelwa yimida. Xa usebenzisa i-rectal suppositories ne-papaverine, ngenxa yokunyusa izinga lokushisa komzimba kunye nokunikezelwa kwegazi okule ndawo, iibhandlela ziyachithwa ngokukhawuleza, kwaye isicatshulwa siyangena kwaye singena kwigazi. Isiphumo esivela kwimiphumo yamakhandlela ngokukhawuleza siza ngokukhawuleza kunokulawula ngomlomo weziyobisi, ngendlela yamacwecwe. Kwakhona, ngale ntshayelelo, le nkunkuma nayo inefuthe elikhulu lendawo. Ngako oko, kunye neentsholongwane ezihamba kakuhle zomzimba wesisu (i-spasm ye-urinary tract, i-spastic colitis, i-cholecystitis), i-intestinal tract, izitho ze-pelvic, i-hemorrhoids, i-papaverine isetyenziswa rhoqo kwikhandlela. Ukongezelela, ukusetyenziswa kwamakhandlela kunye ne-papaverine akunakwenzeka ukuba kwenzeke iziphumo ezibi kunye nokugqithisa.
Ukungqinelana kunye nemiphumo emibi ye-suppositories ne-papaverine
Xa uthatha i-papaverine, ngokukodwa ngesilinganiso esiphezulu, ukunganyanzeliseki komntu, izibomvu kunye nokukhwabanisa kwesikhumba ngenxa ye-vasodilation, utywaba kunye nokulala ngenxa yokunciphisa ngokukhawuleza kwimixinzelelo yegazi, ukucutha kwengxolo yomculo kungabonwa.
Isilwanyana asisetyenziselwa ukuphulwa kwendlela yokuziphatha kwenhliziyo (ukukhutshwa), ukunyuka kwe-intraocular (glaucoma), okwenziwe umonakalo okanye ukungafihli.
Xa usebenzisa i-papaverine, akufanele umsi kwaye uphuze utywala. I-Nicotine yenza ukunciphisa ukusebenza kwechiza, kwaye kakhulu. Ukudibanisa i-papaverine kunye notywala kunokubangela ukuhla kwehla ekuxinzeleleni, ukuphelelwa amandla .
Amakhandlela ane-papaverine e-hemorrhoids
I-pomeverine i-hemorrhoids isetyenziselwa ngokukhethekileyo kuphela kwifom ye-rectal suppositories. Njengoko kukhankanywe ngasentla, ikhandlela elisekwe kwingqungquthela iqalisa ukwenza ngokukhawuleza, ukususa i-spasm nokuvelisa i-anesthhetic effect. Kwakhona, ikhandlela ze-papaverine zinefuthe elincinci, xa i-hemorrhoids ihamba kunye nokuqhaqhazeka. Ukuba isigulane sino-consonpation ye-atonic, ke ukusetyenziswa kwezikhandlela ezinjalo akukhuthazwa, kuba banokuqinisa ukubethelwa kunye nokubangela ukungonakaliswa kwemeko jikelele.
Amakhandlela anepapaverine ekukhulelwe
Nangona imiyalelo kwisizabisi kwaye ibonise ukuba ukusetyenziswa kwayo ngexesha lokukhulelwa kunye ne-lactation ayilunconywa, i-papaverine ezikhandlela idlalwa kubafazi abakhulelweyo ngezwi elongezelelweyo lesisu. Ukuchasana kudibaniswa nefuthe lefuthe le-cardiotoxic kwi-fetus, kodwa xa isilwanyana sisetyenziswe kwizidalwa zonyango, le nto incinci kakhulu. Ngakolunye uhlangothi, ikhandlela ze-papaverine zinefuthe elincinci kakhulu kunye nemiphumo encinci yemiphumo echaphazelekayo xa kuthelekiswa nezinye izalathisi zesi siza.
Indlela yokubeka ikhandlela nge-papaverine?
Ama-suppositories ane-papaverine aveliswa kwisilinganisi se-20 no-40 μg yesilwanyana kwikhandlela elinye. Kuhlala kucebisekile ukuba uqale unyango ngesilinganiso esezantsi, kwaye ukwandise kuphela xa unyango lungasebenzi. Amakhandlela afakwa kwi-anus ukusuka kwi-1 ukuya kwezi-3 ngeentsuku, ngokukhethekileyo emva kokucoca i-rectum, njengalolu hlobo, ukusetyenziswa kweziyobisi kuya kusebenza ngakumbi. Amakhandlela aneepapaverine angasetyenziselwa imihla ngemihla, iikhosi ukuya kwiintsuku ezili-10, okanye iimpawu, ukuba izikhalazo zenzeka. Ixesha elide (ngaphezulu kweentsuku ezili-10) ukusetyenziswa kwansuku zonke kwe-papaverine akukhuthazwa, njengoko kunokubangela ukunyamezela, ukukhathazeka, isisulu, isisu, ukuxuma okugqithiseleyo, ukuphazamiseka kwesisu.