I-De-Nol iyilungiselelo elisebenzayo lokuxuba imithi elisetyenziselwa ukunyanga izifo zesigca esiswini. Amachiza anceda ukuqinisa ukukhuselwa kwe-epithelium ye-mucosa yesisu kunye nokuvuselelwa kwayo emva komonakalo nge-hydrochloric acid eyenziwa ngumzimba. Ubungqina be-De-Nol yesicatshulwa sisenzo sayo sokulwa ne- anti - scythial against chylobacter pylori -ibhaktheriya ebangela i-gastritis, isisu kunye ne-duodenum ulcers.
Ii-analogs kunye nezigqeba zeDe-Nol
Iingqinamba zeeDe-Nol iipilisi ngokwemixube esebenzayo yile:
- Novobispol;
- Biskol;
- I-Biscol-Citrate;
- Ventrisol;
- I-Vis-Nol;
- Duosol;
- Tribimol;
- Ulceron.
Ukwakhiwa kwezi zilungiselelo kubandakanya i-bismuth tricalium dicitrate. Kanye kunye neDe-Nol, izifanisi zayo zinezinto ezinqamlekileyo, ezichasayo nezikhuhlane. Kwimeko ye-acidic yesisu, into esebenzayo, xa ihlanganiswe ne-prostrate yeprotheni, yakha ifilimu ekhuselekileyo kwimimandla ye-erosions kunye neendlela ezinesilonda.
Iimpembelelo ezifanayo zonyango zilawulwa yizakhiwo ezingafaniyo zesipilisi seDe-Nol, esiseqela elifanayo le-pharmological of gastroprotectors. Eyona nto ixhasekileyo phakathi kwabo kukuba:
- Sucralfate;
- ICarbenoxolone;
- Misoprostol;
- Alsukral;
- Sukrat;
- Ulgastan nabanye.
Makhe sinike inkcazo ethelekisayo yeempawu ezingekho komhlaba zonyango lwe-de-Nol.
Sucralfate
I-sucralfate (okanye i-Venter) iqulethe ukusetyenziswa kwayo into esebenzayo-ityhulamu yeruminiyamu, ukwenzela ukuba izidakamizwa zingathathi nto i-bile acids. Kodwa kule meko le nkunkuma ayinakuphumelela ekulweni ne-hylebacter pylori, ayilanga umqobo wokukhusela kwi-epithelium yeendonga zesisu. Ukongeza, i-Sucralfate ineempembelelo ezingaphezulu kunye nokuchasene nokusetyenziswa. Ngoko ke, ngaphezu kwezibambiso eziqhelekileyo, iipilisi akufanele zisetyenziswe kunyango lwabantwana abangaphantsi kweminyaka engama-4 ubudala, i- dysphagia okanye ukuphazamiseka kwendlela yokuxhamla esiswini, ukuphuma kwamagxathu.
ICarbenoksolon
I-Carbenoksolon (okanye i-biogastron) iqukethe into esebenzayo-isicatshulwa kwiingcambu ze-licorice. Isilwanyana sinceda ukwandisa ukugcinwa kwe-muscus eyimfihlo yesisu xa ukwandisa i-viscosity yayo, eyona nto ibangela ukuba kubekho umqobo wokukhusela. Ngaloo xesha kukho imiphumo engathintekanga kwindlela yokuxinzeleleka kwengozi, ukuvuvukala kwamalungu kunye nokuhlamba i-potassium egazini.
Misoprostol
Isidakamizwa seMisoprostol sisisigxina seqela le-prostaglandins - i-hormone-like agents. I-Misoprostol iphucula kakhulu ukuhamba kwegazi kwi-capillaries ye-mucosa yesisu, iyandisa ukwenziwa kwe-mucus, ngelixa iyanciphisa ukukhutshwa kwe-pepsin. Kanye neDe-Nol, i-misoprostol ikhawuleza iinkqubo zokuvuselela kwi-gastritis kunye nesilonda sesisu, kunye ne-duodenum. Xa uthatha isibisi, iimiphumo zengcinezelo zinokwenzeka, ezifana nezo zenzeke ngokusetyenziswa kweDe-Nol.
Iindleko zokuthelekiswa kwezidakamizwa zeDe-Nol kunye nezifana zayo
Kubalulekile ukugxininisa ukuba ezininzi iimpawu zeDe-Nol zibiza kakhulu. Ngokomzekelo, iindleko zesiganeko esithandwayo sesakhiwo seDe-Nol seNovobismol, ngokuqhelekileyo, yi-$ 13, ngelixa ixabiso leethebulethi ze-De-Nol kwiiketyu zeekhemisi zi-1.5 ziphezulu-malunga ne-18 ikiti. Phantse kabini ixabiso lentengo esinye isalathisi esakhiweyo seepilisi ze-Vis-Nol.
Uninzi lweDe-Nol, oluseli qela labaxhamli, lithengisa ngakumbi. Ngoko, iindleko ze-Sucralfate (Venter) zi malunga ne-4 cu. Imbono i-Misoprostol. Esi sisisixhobo esibizayo, intengo yepakethe kunye namacwecwe amathathu afinyelela kuma-$ 50.