Iprolactinum yi-hormone ye-pituitary, ebonelela ukuphuhliswa kweengcambu zamathambo ngexesha lokusasazeka ngexesha lokukhulelwa, ukuvelisa ubisi ngexesha lokuncelisa. Ukunikezela ukuhlalutya kwegazi kwi-hormone prolaktin ugqirha unokuncomela kokubili kubasetyhini kunye namadoda.
Luphi uphando lweprolactin?
Ukunika uhlalutyo lwegazi kwi-hormone yeprolactin kubasetyhini batusa:
- kunye ne-amenorrhea ngaphezu kweenyanga ezintandathu;
- kunye nemigca yeentlanzi zazo ezinobulunga ezifana nobisi, kwabasetyhini abangakhulelwe nabangenayo;
- ngokungahambi;
- ezineentloko ezinzima okanye ukukhubazeka okubonakalayo kwemvelaphi engaziwayo;
- noxinzelelo olunzulu lwangaphakathi;
- nokunyanya.
Uvavanyo lwegazi lweprolactin kumadoda linconywa:
- kunye ne- gynecomastia (ukunyuka kwezilwanyana ezincinci kumama);
- ne-erectile dysfunction;
- eneentloko ezinzima okanye ukukhubazeka okubonakalayo kwe-etiology.
Uhlalutyo lweprolactin - ukulungiselela
Ngomhla wexesha xa uhlalutyo lucwangciselwe i-hormone prolactin, kuyacetyiswa ukuba ugweme uxinzelelo, ukuphepha kwizenzo zesondo, ukuba ungacasuli iimbande zeentlanzi zamathambo. Iiyure ezili-12 phambi kokuvavanywa, akufanele udle, kwaye awukwazi ukutshaya iiyure ezingama-3 phambi kovavanyo. Ukuze ukwazi ukugqithisa kakuhle ukuhlalutya kweprolactin, umele ukhumbule ukuba izinga lehommoni liyakwazi ukuhluka kwimihla yonke kwaye lixhomekeke nakwixa le ntokazi ivukile. Ngoko ke, uhlalutyo kuthathwa phakathi kwe-9 no-10 ekuseni, kodwa akudingeki ukuba uvuke kuze kube ngu-6-7 ekuseni. Iqondo lehomoni egazini lixhomekeke kwisigaba somjikelezo wesini, ngoko ke uhlalutyo lwenziwe ukusuka kwiintsuku ezi-5 ukuya kwezi-8 ukususela ngosuku lokuqala lwenyanga.
Uhlalutyo lwe-hormone prolactin - isisiseko
Kubasetyhini, inqanaba lixhomekeka kubukho bokukhulelwa. Isiqhelo sokuhlalutya kweprolactin kwabasetyhini abangakhulelweyo ngu-4 - 23 ng / ml. Xa ukhulelwe, iziphumo zohlalutyo malunga neprolactin ziya kwahluka - inqanaba leprolactin ngexesha lokukhulelwa landa kakhulu. Ireyithi yabasetyhini abakhulelweyo yindawo ehlukeneyo kwaye ihluka ngoxhomekeke kwiminyaka yobudala ukusuka kwi-34 ukuya kuma-386 ng / ml. Ukukhula kweprolactin egazini labasetyhini abakhulelweyo kuqala kwiiveki eziyi-8, kwaye izinga eliphezulu leprolactin liyabonwa kwiiveki ezingama-20-25. Kubantu, inqanaba leprolactin akufanele lidlule kwi-3 - 15 ng / ml.
Uvavanyo lweprolactin lubonisa ntoni?
Xa uvavanyo lwegazi lweprolactin lufunyenwe, ukulungiswa kwalo kuyenziwa ngugqirha. Akukhuthazwa ukwenza izigqibo ngokuzimeleyo, njengoko izinga lehomoni lixhomekeke kwizinto ezininzi zangaphandle zempembelelo. Ngaphandle kokulungiswa okungafanelekanga ukuhlalutya, ukunyamezela okanye ukukhulelwa okungabonakali kunokubangela ukwanda kwiprolactin, engathethi nasiphi na isifo. Ukuba ugqirha uyathandabuza iziphumo zohlalutyo, unokumisela ukuhlolwa kokukhulelwa okanye ukucela ukubuyiswa kohlalutyo.
Ukuba ukunyuka kwamanqanaba eprolactin akungathandabuzeki, ngoko oku kungabonakalisa izifo ezininzi:
- Iprolactinoma (i-tumor eveza i-hormone ye-pituitary gland), inqanaba leprolactin apho lidla ngaphezu kwama-200 ng / ml. Ezinye iimpawu ziyi-amenorrhea, ukungabikho kolwazi, i-galactorrhea, imbono ephosakeleyo, ikhanda, ukukhuluphala, ukunyuka kwengcinezelo engapheliyo.
- I-Hypothyroidism (ukuhla kwe-thyroid gland), apho izinga legazi kwi-hormone yakhe liyancipha, kunye nokukhuluphala, isikhumba esomileyo, ukuvuvukala,
ukuphazamiseka kokuya esikhathini, ukudandatheka, ukulala nokukhathala. - I-polycystic ovary , eya kubandakanya ukuphulwa komjikelezo wesini, i-hirsutism, ukungabikho komntwana.
- Ezinye izifo apho iprolactin iphuma - i-anorexia, i-cirrhosis, isifo sesifo, isifo se-hypothalamus.
Ukunciphisa kwinqanaba leprolactin lisoloko lugqirha kwaye lugcinwa rhoqo emva kokuba kuthathe imithi ethile (iDopamine, i-Levodopa), kodwa ingaba yimiqondiso yezifo ezifana nezicubu kunye nesifo sofuba se-pituitary gland, kwakunye nesiphumo senxeba okanye inkunkuma ye-pituitary.