Iimvumi zesibindi

Ii-enzymes zesibindi - le ngenye yezona zinto zibaluleke kakhulu kwiinkqubo ze-biochemical emzimbeni. Ekubeni isibindi senza imisebenzi eninzi, i-enzymes eyenziwe yinto ehlukeneyo ngamaqela amaninzi: i-excretory, isalathisi kunye nemfihlo. Ngenxa yezifo ezahlukahlukeneyo kunye nomonakalo wesibindi kwi-plasma yegazi, umxholo we-enzyme utshintsha. Le ngxaki ibalulekileyo isalathisi sokuxilonga.

Ziziphi i-enzyme zesibindi ezisetyenziselwa ukuxilongwa?

Ii-enzyme zesibindi, umxholo onganyuswa kwizifo ezihamba kunye nokutshatyalaliswa kwe-hepatocytes, zibizwa ngokuba yi-enzyme ye-indicator. Ezi ziquka:

• glutamate dehydrogenase (Gldg);
• i-aspartate aminotransferase (AST);
• i-lactate dehydrogenase (i-LDH);
• i-gamma-glutamyltransferase (GGT);
• alanine aminotransferase (ALT).

Ngokuqhelekileyo, isifo sesibindi sichazwe ukuhlolwa kwegazi ngokuzimisela komxholo we-AST kunye ne-ALT. Kubafazi, umgangatho we-ACT ngowama-20-40 U / l. Ngomonakalo obuthakathaka okanye umonakalo kwi-hepatocytes, ezi nzyzy zandisa kakhulu umsebenzi.

Isiqhelo somxholo we-enzyme yesibindi i-ALT egazini yi-12-32 U / l (ibhinqa). Ngezifo ezithathelwanayo, imisebenzi yabo iyanda kakhulu - kwixesha elininzi. Kule meko, iimpawu zeklinikhi zesi sifo zingasekho. Yingakho i-ALT idla ngokuphindaphindiweyo ukufumanisa i-hepatitis ekuqaleni kwexesha.

Esinye isixhobo sokuxilonga yi-Ritis coefficient (ratio ye-AST / ALT). Kumntu onempilo, ngu-1.3.

Izilingo ezongezelelweyo ze-enzymes

Ukuqhuba ukwahlula ngokuchanekileyo kwezifo, i-laboratory inokuphinda ihlolisise uhlalutyo kwaye ifumene zonke i-enzyme ezinobindi egazini. Kwizilonda ezahlukeneyo zesibindi, izifo ze-oncological, ubuthi obubi kunye nezifo ezithintekayo, isigulane sikaGldg isiguli ( umgangatho kufuneka ube ngaphantsi kwama-3.0 U / l kwabasetyhini). Ukwandisa inzyme yesibindi GGT egazini (ngaphezu kwe-38 U / l)? Oku kusoloko kubonisa ukuba isiguli sinesifo se-buct okanye isifo sikashukela .

Ingxenye ye-enzyme yesibindi ifihliwe kwiidrophu ze-bile. Benza inxaxheba ekutyeni. I-enzyme enjalo i-alkaline phosphatase. Ngokuqhelekileyo umxholo weesalathisi zomhlaba we-alkaline akufanele kudlule i-120 U / l. Kodwa ukuba iinkqubo zokuxiliswa kweempawu eziphambene nomzimba ziphulwa, le ncwadana ikhula malunga no-400 U / l.