Enye yezidakamizwa ezithandwa kakhulu kwi-anti-virus kunye ne-immunomodulating drugs, i-Interferon Alpha, yinto yemveliso yobunjineli. Isekelwe kwiprotheni ehlanjululweyo, engumzekelo we-protein yegazi lomntu kwaye kuthiwa yi-interferon. Ingaba yimizekelo emininzi, kodwa izilungiso ezisusela kwiiprotheyini ze-alferenethi ziyaziwa ngokuphezulu.
Ifomu yokukhululwa kwe-Interferon Alpha
Kukho iindlela ezininzi zokusebenzisa iziyobisi, ngoko ukukhutshwa kweendlela ezahlukeneyo zeziyobisi kulungelelaniswa ne-pharmacologically:
- I powder eyomileyo esetyenziselwa ukujova kunye kunye namanzi adibeneyo;
- isisombululo esilungele ukujova;
- i-rectal suppositories;
- mafutha;
- amaconsi;
- spray ;
- kwehla kwemehlo;
- umquba oomileyo wokulungiswa kwamaconsi kunye neso.
Ukusetyenziswa kwe-Interferon Alpha
Unyango kunye ne-Interferon Alpha isekelwe kwimpembelelo ephezulu ye-anti-virus. Kuye kwadluliwe ukuba umntu ovelisa intsholongwane emzimbeni akanako ukusulelwa yintsholongwane. Ngokusungulwa kwe-interferon, iiseli apho inqatsholongwane engangenanga khona, ingakwazi ukumelana nalo kwaye ekugqibeleni isifo siya. Ekubeni eli cwangciso lifanelekileyo kwiintsholongwane zaluphi na uhlobo, ububanzi be-Interferon Alpha bubanzi kakhulu:
- i-hepatitis yentsholongwane nayiphi na uhlobo;
- i-conjunctivitis;
- izifo zonyango kunye nesifo sofuba;
- SARS , umkhuhlane;
- papillomatosis;
- multipleeloma;
- leukemia;
- Sarcoma Kaposi;
- lymphoma;
- i-carcinoma;
- iintsholongwane zentsholongwane kunye ne-bactericidal-viral yaluphi na uhlobo kubantwana.
Ngokungafani nezinye izidakamizwa ze-anti-virus ezivela kwimvelaphi yokwenziwa, i-interferon inokuphikisana okumbalwa. Isetyenziswe ngokuqapha kwiimeko zeengxaki kunye nezitho zokuphuma kunye nezinye izifo zesibindi. Ngethuba lokukhulelwa kunye ne-lactation le nkunkuma ithathwa ngokungqongqo ngokwemiqathango yonyango. Imiphumo emibi ye-Interferon Alpha ayikwazi ukubizwa ngokuba mnandi, kodwa ayinqabile. Ezi zi:
- ukuphosa;
- umkhuhlane;
- isicefe
- kulala.
Kwakhona kubalulekile ukwazi ukuba le nyilisi ayihambelani kakhulu kunye namanye amayeza kunye nemichiza, ngoko kufuneka uxoxe nomgqirha malunga nokusebenzisa nganye. Oku kuya kunceda ukuphepha iingxaki ezinzulu. Kuyinto engathandekiyo ukuthatha i-interferon kunye kunye nezidakamizwa kunye nezidakamizwa.
Indlela yokwenza i-Interferon Alpha nge powder, kuxhomekeke kwiinjongo. Umthamo ofunekayo wesilwanyana kufuneka uhlanjululwe ngaphambili ngamanzi adibeneyo ukwenzela injola kwisixa sama-50 ml. Xa ufuna ukuhla kwempumlo, okanye amehlo, unokusebenzisa i-saline (i-sodium chloride) kule njongo.
Iliso lehla i-Interferon Alpha kunye nezinye iindidi zamachiza zilungele ukusetyenziswa kwaye azidingi ukongezwa kwezinto ezongezelelweyo.
Iintetho ze-Interferon Alpha
Ukwangoku, kukho ezininzi iziyobisi ezisekelwe kwii-interferons ezahlukeneyo. Ezinye zazo zivela kwimvelaphi yokungenisa, ezinye zivela kwimvelaphi yasekhaya, kodwa iqondo lokusebenza kwazo zonke ezi mayeza lilinganayo. Umehluko kuphela umgangatho weproteyini yokuhlanjululwa kwaye, ngoko ke, ixabiso. Nalu uluhlu lwemithi enokuthi ithathe indawo ye-Interferon Alpha:
- Alfarekin;
- Intron A;
- Roferon;
- Nasoferon;
- Vellveron;
- i-interferon leukocyte yabantu kunye nabanye.
Zonke ezi machiza zenzelwe ukuphatha imbonakalo yee-virus ezahlukeneyo, ukuvimba ukusabalala komzimba, ukuthintela ukusuleleka kweeseli ezintsha, ukuqinisa i-membrane yeseli. Ngenxa yokuqulunqwa kwee-enzyme zoluhlobo olukhethekileyo, umzimba uqinisa umzimba womzimba kwaye uqala ukulwa okuzimeleyo malunga nokusuleleka. Kwakhona i-intelferoni yazo zonke iintlobo zinemiphumo yokuchasana, izizathu ezingenakuchongwa ngokuchanekileyo ukuba zifikelele, nangona kunjalo, ukusetyenziswa kwezilwanyana kunyango nokukhusela umhlaza akuvumelekanga.