I-AST isicatshulwa se-aspartate aminotransferase, i-enzyme ye-intracellular edlala indima ebalulekileyo kwi-metabolism yamino acid. I-enzyme ibonisa umsebenzi omkhulu kunazo zonke kwiinkqubo zokuxilonga, ezenzeka kwiimfucu zesibindi, izintso, intliziyo, izihlunu zamasipha kunye nezinye iziphetho zentsholongwane.
Uvavanyo lwegazi lwe-AST luqhelekileyo kubafazi
Umgangatho oqhelekileyo we-AST egazini labesetyhini uthathwa njengezinga leenqununu ezingama-20 ukuya kuma-40 nganye ngeyure. Kule meko, izibonakaliso ezisezantsi ziyakwenzeka, kwaye inkalo yenkqubo enzulu ye-pathological index i-AST ingaphantsi kwama-5 iyunithi nganye. Izalathisi ezandisiweyo zithathwa njengezifanelekile ukuba ingqalelo ukuba umda ungadluli kwiiyunithi ezingama-45 kwithayitha.
Kwakhona, ekuhlaleni kwinqanaba le-AST kwabasetyhini, kuyafaneleka ukuphawula ukuba izinga lakhe lixhomekeke kwiminyaka yobudala. Ngoko, ukufikelela kwiminyaka eyi-14, isibonakaliso sithathwa njengama-unit units angama-45, ekunciphiseni kwayo kancane kancane. Kwaye kuphela kwimizuzu engama-30 umda ophezulu wesigqeba isetyenziswe kwiiyunithi ezingama-35-40 ngeyure nganye.
Ukongezelela, kufuneka kuphawulwe ukuba kwiyeza, iindlela ezininzi zisetyenziselwa ukucacisa le ncwadana, kwaye iimpawu eziqhelekileyo ziyahlukahluka kuxhomekeke kulowo usetyenziswayo. Ngoko ke, ukuchazwa kohlalutyo kufuneka kwenziwe yinkwenkwezi.
Inqanaba eliphantsi le-AST egazini
Iimeko xa izinga le-AST egazini lingaphantsi kuneqhelekileyo, kokubili kwabesetyhini kunye namadoda, aluqhelekanga, kwaye kukholelwa ukuba isibonakaliso esinjalo asinayo ibalulekileyo yokuxilonga. Oku kubangelwa ukuba umda ophantsi wesalathisi oqhelekileyo ulungele ukuphazamiseka, kwaye kunye ne-indicator yeeyunithi ezi-10 ukuya ku-15 ayikwazi ukuqwalaselwa njengento echanekileyo yobungqina bentlalo.
Ukuncipha kwinqanaba le-AST kungakho ngenxa yokuba:
- ukuphelelwa ngokubanzi;
- ukungabikho kwe vithamini B6 ;
- isigaba sokugqibela se-cirrhosis okanye esinye isona somonakalo obunzima (ukuhla ngokukhawuleza kwiingqungquthela, ngaphantsi kwama-5 kwiyure nganye).
Ukwandisa izinga le-AST egazini
Ngokubanzi, iikhompyutheni ezikhulayo ze-AST zihlala zihlala zihlala zihlala zize zibonise:
- i-cirrhosis, i-hepatitis enzima (ngokuqhelekileyo uMthetho uyagxuma ibalulekileyo yaye ungadlulela kwisiganeko ngamaxesha angaphezu kwama-20);
- i-dystrophy ye-muscular kunye ne-dermatomyositis (ngaphezu kwexesha eliqhelekileyo ngamaxesha angama-8);
- i-pancreatitis ephazamisayo , izifo zegazi, izigaba zokuqala zesigqirha (2-5-i-fold over);
- i-thromboembolism ye-pulmonary umthambo (ngaphezu kwesiqhelo ngo-2-3 amaxesha).
Ukongeza kwiingxaki ezingentla, ukwanda kwinqanaba le-AST kubonakala ekuhlaselweni kwe-angina kunye nokungaphumeleli kwentliziyo.