I-thyroxine yamahhala, i-hormone eveliswa yi-hypothalamus, ibaluleke kakhulu ekuqinisekiseni ukusebenza ngokuqhelekileyo kwe-thyroid gland. Uninzi lweqhezu le-hormone i-T4 alunxulumene namaprotheni abathwala, yingakho igama layo "likhululekile i-thyroxine" lichazwe.
Ukuhlolwa kwegazi kwi-thyroxine yamahhala
I-T4 ichaphazela umzimba womntu ngale ndlela:
- ukwandisa ukusetshenziswa kwe-oksijini ngamaseli;
- ubeka umgangatho weetabolism kwizicubu;
- kucima imilambo ye-cholesterol eyingozi;
- ikhuthaza ukuhlanganiswa kweeprotheni;
- i thintesis;
- uqinisekisa ukuphuhliswa okuqhelekileyo kunye nokukhula;
- ixhasa inkqubo yokwakha ubushushu.
Ukongezelela, i-hormone ye-T4 ichaphazela amandla omfazi ukuba akhulelwe, anyamezele aze abelethe umntwana ophilileyo. Ngokumalunga nokubaluleka kwehomoni ebomini bomzimba, kubalulekile ukwazi ukuba i-thyroxine yamahhala iyinto evamile. Ukumisela i-thyroxine yamahhala kwi-plasma yegazi kwibhubhoratri yinkampu yegazi.
I-Norm ye-thyroxine ikhululekile incike kwisini kunye nobudala. Kwamadoda, umxholo wehommone uphakame kakhulu kunabesifazane. Amanqanaba aqhelekileyo e-T4 kwabasetyhini anjengale ndlela:
- eneminyaka eyi-14 ukuya kwe-40 iminyaka-100-120 nM / l;
- emva kweminyaka engama-40 - 80-100 nM / l.
Kubabhinqileyo abakhulelweyo, ingxube ye-thyroxin yamahhala i-120-140 nM / L, kwaye oku kubangelwa kukuba inxalenye yehomoni yomama iya kwindlela yokwenza ithambo lomntwana. Ukuxhomekeka kwimixholo egazini le-T4 ngexesha lemihla kunye nexesha lonyaka lwakhiwe.
Ibanga eliphezulu liphawulwe:
- Ngo-Oktobha noFebruwari;
- ukusuka ku-8-00 ukuya ku-12-00.
Ixabiso elincinci li:
- ngoJuni-Agasti;
- ukusuka ku- 23-00 ukuya ku-3-00.
Ukwandisa umxholo we-thyroxine wamahhala
I-thyroxine yamahhala yanda:
- myeloma ;
- umonakalo wezintso;
- izifo zesibindi, kubandakanywa nabo abane-hepatitis;
- utshintsho olunzulu kwi-thyroid gland yeSiseko seSiseko kunye nesifo se-Graves;
- ukuphulwa kweenkqubo zeempawu;
- ubunzima bomzimba obuninzi.
Kwakhona, ukwanda kwinqanaba le-hormone T4 lingavela ngenxa yonyango lwezonyango zomzimba, kunye nokutya okungalunganga kwamalungiselelo enzonyango (Aspirin, Danazol, Levotheoxin, Furosemidonoma, njl.) Kunye nokusetyenziswa okungalawulwayo kwe-Heparin kwonyango lwe-thrombosis.
I-thyroxine ikhululekile
Umxholo we-thyroxin yamahhala ngaphantsi kwesiqhelo ufana neemeko nezifo njenge:
- ngokugqithiseleyo;
- ukutya kweprotheni ukulahleka kwesisindo;
- iimeko zengcinezelo ezide;
- ukungahambi kwe-iodine;
- goiter;
- hypothyroidism ;
- izicubu ze-thyroid;
- ukuvuvukala kwesigwebe se-pituitary;
- i-craniocebral trauma;
- khokela utyhefu.
Ngamanye amaxesha i-thyroxin ye-free ehlulwayo iyaqaphela xa ithabatha amachiza, kuquka:
- ukusetyenziswa ngokugqithiseleyo kwezidakamizwa ezithile ezixinzelelekileyo;
- ukugqithisa kwe-Clofibrate kunye neminye imithi ehlaziya igazi;
- ukusetyenziswa kwezicoco zomlomo;
- ukusetyenziswa kwe-anti-tuberculosis, i-anti-inflammatory, i-anticonvulsant izidakamizwa, i-glucocorticoids kunye neziyobisi ukwenzela unyango lwe-goiter eyingozi.
Nceda nceda! Ukuhla kwe-T4 kunokubonisa ukuba isigulane sithatha izidakamizwa eziqukethe izinto!
Khanyisa utshintsho kwimixholo ye-thyroxine yamahhala egazini - kungekhona ithuba lokuxhalabisa, kodwa utshintsho oluphawulekayo kwiimeko ze-hormonal kunye nokuhlaselwa komgangatho wezempilo kufuna ukuhlolwa kweengcali. Ngoko, ukuze kuqinisekiswe ukuguqulwa kweenguqu kwizinga le-T4 yamahhala kwizifo ze-thyroid, kucetyiswa ukuba unikele ngegazi kathathu ngenyanga kwimizuzu emibini.